Protein Alignment bw and w

DIOPT Version :10

• Sequence 1: NP_523824.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_061509581.1
• Gene: w / 1271671
• VectorBaseID: AGAMI1_013186
• Length: 722
• Species: Anopheles gambiae
• Alignment Length: 742
• Identity: 199/742 - (26%)
• Similarity: 318/742 - (42%)
• Gaps: 196/742 - (26%)

  Fly    19 WKQLNY-----YVPDQEQSNYSFWNE------------------------CRKKRE-----LRIL 49
            ||..:|     .:|..|:..|: |.|                        |.::|:     ..:|
Mosquito    53 WKPKSYGSVKGQIPQCERLTYT-WKEIDVFGEAPTDGKPREPLCTRLRNCCTRQRKDFNPRKHLL 116

  Fly    50 QDASGHMKTGDLIAILGGSGAGKTTLLAAISQR----LRGNLTGDVVLNGMAMERHQMTRISSFL 110
            ::.:|..|:|:|:|::|.|||||||||.|::.|    ::.:......|||:.:...|:....:::
Mosquito   117 KNVTGVAKSGELLAVMGSSGAGKTTLLNALAFRSPPGVKISPNAVRALNGVPVNAEQLRARCAYV 181

  Fly   111 PQFEINVKTFTAYEHLYFMSHFKMHRRTTKAEKRQRVADLLLAVGLRDAAHT------RIQQLSG 169
            .|.::.:.:.|..|||.|.:..:|.|....:.|:.||.::|..:.|...|.|      ||:.|||
Mosquito   182 QQDDLFIPSLTTREHLLFQAMLRMGRDVPASVKQHRVQEVLQELSLVKCADTIIGAPGRIKGLSG 246

  Fly   170 GERKRLSLAEELITDPIFLFCDEPTTGLDSFSAYSVIKTLRHLCTRRRIAKHSLNQVYGEDSFET 234
            ||||||:.|.|.:|||..|.|||||:|||||.|:||::.|:
Mosquito   247 GERKRLAFASETLTDPHLLLCDEPTSGLDSFMAHSVLQVLK------------------------ 287

  Fly   235 PSGESSASGSGSKSIEMEVVAESHESLLQTMRELPALGVLSNSPNGTHKKAAICSIHQPTSDIFE 299
                    |...|.                                   |..|.:||||:|:::.
Mosquito   288 --------GMAMKG-----------------------------------KTIILTIHQPSSELYC 309

  Fly   300 LFTHIILMDGGRIVYQGRTEQAAKFFTDLGYELPLNCNPADFYLKTLADKEGKEN---------- 354
            ||..|:|:..||:.:.|...|:|:||:.||...|.|.||||||::.||....||.
Mosquito   310 LFDKILLVAEGRVAFLGSPYQSAEFFSQLGIPCPPNYNPADFYVQMLAIAPAKEAECRDMIKKIC 374

  Fly   355 ------------------AGAVLRAKYE-HETDGL----YSGSW------LLARSYSGDYLKHVQ 390
                              ||..:...|. .:.:|:    |..||      :|.||:        .
Mosquito   375 DSFAVSPIAREVLETASVAGKGMDEPYMLQQVEGVGSTGYRSSWWTQFYCILWRSW--------L 431

  Fly   391 NFKKIRWIYQVYLLMV----RFMTEDLRNIRSGLIAFGFF------MITAVTLSLMYSGIGGLTQ 445
            :..|...:.:|.||..    |..:.||..:.:   .|..|      |:..:..|:.:..:  |.|
Mosquito   432 SVLKDPMLVKVRLLQTAVGSRGPSSDLPELTT---CFPCFFSPRPQMVATLIGSIYFGQV--LDQ 491

  Fly   446 RTVQDVGGSIFMLSNEMIFTFSYGVTYIFPAALPIIRREVGEGTYSLSAYYVALVLSFVPVAFFK 510
            ..|.::.||:|:....|.|...:.|..:|.|.||:..||.....|.:..|::...::.:|:....
Mosquito   492 DGVMNINGSLFLFLTNMTFQNVFAVINVFSAELPVFLREKRSRLYRVDTYFLGKTIAELPLFIAV 556

  Fly   511 GYVFLSVIYASIYYTRGFLLYLSMGFLMSLSAVAAVGYGVFLSSLFESDKMASECAAPFDLIFLI 575
            .:||.|:.|..|....|...||:..|:::|.|..:..:|..:|....|..||.....|..:.|||
Mosquito   557 PFVFTSITYPMIGLRTGATHYLTTLFIVTLVANVSTSFGYLISCASSSISMALSVGPPVVIPFLI 621

  Fly   576 FGGTYMNVDTVPG----LKYLSLFFYSNEALMYKFWIDI---------DNIDCPVNEDHPCIKTG 627
            |||.::|..:||.    |.|||.|.|:||||:...|..:         .|:.||        ::|
Mosquito   622 FGGFFLNSASVPAYFKYLSYLSWFRYANEALLINQWSTVVDGEIACTRANVTCP--------RSG 678

  Fly   628 VEVLQQGSYRNADYTYWLDC-FSLVVV 653
            ..:|:..::|..|:...:.| |:|:|:
Mosquito   679 EIILETFNFRVEDFALDIACLFALIVL 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_523824.1	3a01204	40..673	CDD:273361	191/692 (28%)
w	XP_061509581.1	None