Protein Alignment bw and Abcg1

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_033723.1
• Gene: Abcg1 / 11307
• MGIID: 107704
• Length: 666
• Species: Mus musculus
• Alignment Length: 697
• Identity: 172/697 - (24%)
• Similarity: 302/697 - (43%)
• Gaps: 156/697 - (22%)

  Fly    17 LEWKQLNYYVPDQEQSNYSFWNECRKKRELRILQDASGHMKTGDLIAILGGSGAGKTTLLAAISQ 81
            :|:|.|:|.||:.     .:|   :||....:|:..||...:|:|:||:|.|||||:||:..::.
Mouse    77 IEFKDLSYSVPEG-----PWW---KKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAG 133

  Fly    82 RLRGNLTGDVVLNGMAMERHQMTRISSFLPQFEINVKTFTAYEHLYFMSHFKMHRRTTKAEKRQR 146
            .....:.|.|::|||..:.....::|.::.|.::.:...|..|.:...:|.|:..:  ...:|:.
Mouse   134 YRETGMKGAVLINGMPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEK--DEGRREM 196

  Fly   147 VADLLLAVGLRDAAHTRIQQLSGGERKRLSLAEELITDPIFLFCDEPTTGLDSFSAYSVIKTLRH 211
            |.::|.|:||...|:||...||||:||||::|.||:.:|..:|.||||:||||.|.:.|:..::.
Mouse   197 VKEILTALGLLPCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKG 261

  Fly   212 LCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSKSIEMEVVAESHESLLQTMRELPALGVLSN 276
            |                              ..|.:||
Mouse   262 L------------------------------AQGGRSI--------------------------- 269

  Fly   277 SPNGTHKKAAICSIHQPTSDIFELFTHIILMDGGRIVYQGRTEQAAKFFTDLGYELPLNCNPADF 341
                      :|:||||::.:||||..:.::..|:.||:|:......:..|||...|...|||||
Mouse   270 ----------VCTIHQPSAKLFELFDQLYVLSQGQCVYRGKVSNLVPYLRDLGLNCPTYHNPADF 324

  Fly   342 YLKTLADKEGKENAGAVLRAKYEHETDGLYSGSWLLARSYSGD-----YLKH------------V 389
            .::..:.:.|.:|: .::||..|...|..|.      |...||     :|.|            .
Mouse   325 VMEVASGEYGDQNS-RLVRAVREGMCDADYK------RDLGGDTDVNPFLWHRPAEEDSASMEGC 382

  Fly   390 QNFKKIRWIYQVYLLMVRFMTEDLR-----------NIRSGLIAFGFFMITAVTLSLMYSGIGGL 443
            .:| ....:.|..:|..|.....:|           :|..||:           :.|:|.|||..
Mouse   383 HSF-SASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLL-----------IGLLYLGIGNE 435

  Fly   444 TQRTVQDVGGSIFMLSNEMIFTFSYGVTYIFPAALPIIRREVGEGTYSLSAYYVALVLSFVPVAF 508
            .::.:.: .|.:|.....::|.........||..:.:..||.....|||.|||:|..::.||.
Mouse   436 AKKVLSN-SGFLFFSMLFLMFAALMPTVLTFPLEMSVFLREHLNYWYSLKAYYLAKTMADVPF-- 497

  Fly   509 FKGYVFLSVIYASIYY--------TRGFLLYLSMGFLMSLSAVAAVGYGVFLSSLFESDKMASEC 565
               .:...|.|.||.|        ...|:|:.::|.:.||   .|...|:.:.:...|.::|:..
Mouse   498 ---QIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSL---VAQSLGLLIGAASTSLQVATFV 556

  Fly   566 AAPFDLIFLIFGGTYMNVDTVPG----LKYLSLFFYSNEALMYKFW-IDIDNIDCPVNEDHPC-I 624
            .....:..|:|.|.:::.||:|.    :.|:|...|..|.::...: :|.:::.|.:.|  .| .
Mouse   557 GPVTAIPVLLFSGFFVSFDTIPAYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIAE--TCHF 619

  Fly   625 KTGVEVLQQGSYRNADYTYWLDCFSLVVVAVIFHIVSFGLVRRYIHR 671
            :....:|::....||  ..:||   .:|:.:.|  :|..|:..::.|
Mouse   620 QKSEAILRELDVENA--KLYLD---FIVLGIFF--ISLRLIAYFVLR 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	77/284 (27%)
		3a01204	40..673	CDD:273361	165/674 (24%)
		ABC2_membrane	404..604	CDD:279410	51/222 (23%)
Abcg1	NP_033723.1	3a01204	60..666	CDD:273361	172/697 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820