Protein Alignment bw and Abca2

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_006497672.1
• Gene: Abca2 / 11305
• MGIID: 99606
• Length: 2464
• Species: Mus musculus
• Alignment Length: 613
• Identity: 123/613 - (20%)
• Similarity: 219/613 - (35%)
• Gaps: 185/613 - (30%)

  Fly    49 LQDASGHMKTGDLIAILGGSGAGKTTLLAAISQRLRGNLTGDVVLNG--MAMERHQMTRISSFLP 111
            |...|.::....:::.||.:||||||.::.:: .|....:|...:.|  :..|..::.:.....|
Mouse  1037 LNKLSLNLYENQVVSFLGHNGAGKTTTMSILT-GLFPPTSGSATIYGHDIRTEMDEIRKNLGMCP 1100

  Fly   112 QFEINVKTFTAYEHLYFMSHFK-MHRRTTKAEKRQRVADLLLAVGLRDAAHTRIQQLSGGERKRL 175
            |..:.....|..|||:|.|..| |.:...:.|..:.:.||.|:    :..|:.:|.||||.:::|
Mouse  1101 QHNVLFDRLTVEEHLWFYSRLKSMAQEEIRKETDKMIEDLELS----NKRHSLVQTLSGGMKRKL 1161

  Fly   176 SLAEELITDPIFLFCDEPTTGLDSFS-------------AYSVIKTLRH------LCTRRRIAKH 221
            |:|...:.....:..||||.|:|.::             ..:::.:..|      |..|..|..|
Mouse  1162 SVAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGDRIAIISH 1226

  Fly   222 SLNQVYGEDSFETPSGESSASGSGSKSIEMEVVAESHESLLQTMRELPALGVLSNSPNGTHKKAA 286
            ...:..|     :|.....|.|.|.:...::..||...|      :.|.   |::||:|..:.::
Mouse  1227 GKLKCCG-----SPLFLKGAYGDGYRLTLVKQPAEPGTS------QEPG---LASSPSGCPRLSS 1277

  Fly   287 ICSIHQPT-------------SDIFELFTHIILMDGGRIVYQGRTEQAAKFFTDLGYELP----- 333
             ||..|.:             ||.....::|:..:.   |.:|..|   :.|..|.:.|.
Mouse  1278 -CSEPQVSQFIRKHVASSLLVSDTSTELSYILPSEA---VKKGAFE---RLFQQLEHSLDALHLS 1335

  Fly   334 ----LNCNPADFYLKTLADKEGKENAGAVLRAKYEHETDGLYSGSWL---------LAR------ 379
                ::....:.:||...:.:..||:.|.::   |...|.|.....|         |||
Mouse  1336 SFGLMDTTLEEVFLKVSEEDQSLENSEADVK---ESRKDVLPGAEGLTAVGGQAGNLARCSELAQ 1397

  Fly   380 --------------------SYS---GDY----------------------LKHV-QNFKKIR-- 396
                                .||   |||                      |..| |..:|:.
Mouse  1398 SQASLQSASSVGSARGEEGTGYSDGYGDYRPLFDNLQDPDNVSLQEAEMEALAQVGQGSRKLEGW 1462

  Fly   397 WI--YQVYLLMVRFMTEDLRNIR---SGLIAFGFFMITAVTLSLMYSGIGGLTQRTVQ------- 449
            |:  .|.:.|:|:......||.:   |.::...||:..|:|::|....||.|....:.
Mouse  1463 WLKMRQFHGLLVKRFHCARRNSKALCSQILLPAFFVCVAMTVALSVPEIGDLPPLVLSPSQYHNY 1527

  Fly   450 -DVGGSIFMLSNE-----------------MIFTF----SYGVTYIFPAAL-----PIIRREVGE 487
             ...|:....:||                 ::.||    ..|.|.:..:..     |::....||
Mouse  1528 TQPRGNFIPYANEERQEYRLRLSPDASPQQLVSTFRLPSGVGATCVLKSPANGSLGPMLNLSSGE 1592

  Fly   488 GTYSLSAYYVALVL----------SFVP 505
            .....:.::.::.|          :|||
Mouse  1593 SRLLAARFFDSMCLESFTQGLPLSNFVP 1620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	68/301 (23%)
		3a01204	40..673	CDD:273361	123/613 (20%)
		ABC2_membrane	404..604	CDD:279410	27/149 (18%)
Abca2	XP_006497672.1	rim_protein	58..2398	CDD:130324	123/613 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000