Protein Alignment bw and abcg8

DIOPT Version :10

• Sequence 1: NP_523824.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001108041.3
• Gene: abcg8 / 100136850
• ZFINID: ZDB-GENE-050517-41
• Length: 676
• Species: Danio rerio
• Alignment Length: 751
• Identity: 168/751 - (22%)
• Similarity: 307/751 - (40%)
• Gaps: 209/751 - (27%)

  Fly     4 SGGSSGQGGPSLCLEWKQLNYYVPDQEQSN-YSFWNECRKKRELR-----ILQDASGHMKTGDLI 62
            |||.:.       ||.:.|||.|....|.. |...:|.:...|:.     :::|.:.|:.:|.::
Zfish    42 SGGRNE-------LEVRNLNYEVDTAAQIPWYEKLSEFKMPWEMHSNKQTVIKDLNLHVHSGQML 99

  Fly    63 AILGGSGAGKTTLLAAISQRLRGNL--TGDVVLNGMAMERHQMTRISSFLPQFEINVKTFTAYEH 125
            |::|.||.|||:||..|:.|..|..  :|::::||....|..:.:..:.:.|.:..:...|..|.
Zfish   100 AVIGSSGCGKTSLLDIITCRDEGGSMNSGEILINGKPSTRSLVKKSIAHVRQDDRLLPHLTVRET 164

  Fly   126 LYFMSHFKMHRRTTKAEKRQRVADLLLAVGLRDAAHTR-----IQQLSGGERKRLSLAEELITDP 185
            |.|::..::....::.::.|||.|::..:.||..||||     ::.:|||||:|:|:|.:|:.:|
Zfish   165 LAFVAKLRLPANFSQKQRDQRVDDVIAELRLRQCAHTRVGNEYVRGVSGGERRRVSIAVQLLWNP 229

  Fly   186 IFLFCDEPTTGLDSFSAYSVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSKSIE 250
            ..|..||||:|||||:|::::.||..|....|:
Zfish   230 GILILDEPTSGLDSFTAHNLVITLYRLARGNRL-------------------------------- 262

  Fly   251 MEVVAESHESLLQTMRELPALGVLSNSPNGTHKKAAICSIHQPTSDIFELFTHIILMDGGRIVYQ 315
                                               .:.|:|||.||||:||..::|:..|..||.
Zfish   263 -----------------------------------VLLSVHQPRSDIFQLFDLVVLLSSGSAVYC 292

  Fly   316 GRTEQAAKFFTDLGYELPLNCNPADFYLKTLADKEGKENAGAVLRAKYEHETDGLYSGSWLLARS 380
            |:.:....:||.|||..|..|||:|:|:..:          ::.|...|.|...|...|.|.|:
Zfish   293 GQAKDMVSYFTTLGYPCPRYCNPSDYYVDLI----------SIDRRTPEKEAQCLEKASMLAAQ- 346

  Fly   381 YSGDYLKHVQNFKKIRW---------------------------------------IYQVYLLMV 406
                :|:.|:|.:...|                                       ::|...|:.
Zfish   347 ----FLEKVKNNEDFMWKSEVCGPPALEAPQSSVPSVSMKESVITVSKQKDQLPGKVHQFTTLIR 407

  Fly   407 RFMTEDLRNIRSGLIAFGFFMITAVTLSLMYSGIG----GLTQR--TVQDVGGSIFMLSNEMIFT 465
            |.:..|.|::.: |:..|   :.|:.:||:   ||    |.|:.  ::||....::|:
Zfish   408 RQVFNDYRDLVT-LVVHG---LEALLMSLL---IGFLYFGCTEEGLSIQDTVALLYMI------- 458

  Fly   466 FSYGVTYIFPAALPIIRR----------EVGEGTYSLSAYYVALVLSFVPVAFFKGYVFLSVIYA 520
               |....|...|.:|.:          |:.:|.||::.|:.|.||..:|    :...|..|...
Zfish   459 ---GALTPFAVVLDVIAKCHSERAMLYHELEDGMYSVTPYFFAKVLGELP----EHCAFTLVYGV 516

  Fly   521 SIYYTRG-------FLLYLSMGFLMSLSAVAAVGYGVFLSSLFESDKMASECAAPFDLIFLIFGG 578
            .||:..|       |||..   .|:.|:...:....:|:::...:.:.:|........:|.:..|
Zfish   517 PIYWLAGLNVAPDRFLLNF---LLVWLTVYCSRSMALFVAAALPTLQTSSFMGNALFTVFYLTAG 578

  Fly   579 TYMNVDTV----PGLKYLSLFFYSNEALMY------KFWIDIDNIDCPVNEDHPCIKTGVEVLQQ 633
            ..::::.:    ....|:|...:..|.::.      :..|.|.|:    ..:...||. ||:::.
Zfish   579 FVISLENMWMVASWFSYISFMRWGFEGMLQVQFRGTRIPITIGNL----TVEFDGIKV-VEMMKM 638

  Fly   634 GSYRNADYTYWLDCFSLVVVAVIFHIVSFGLVRRYI 669
            ..|.      ...|:.:::...:..|:.:.|..::|
Zfish   639 NQYP------LFSCYLVLIAVSLVFILLYYLSLKFI 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_523824.1	3a01204	40..673	CDD:273361	156/714 (22%)
abcg8	NP_001108041.3	None