Protein Alignment seq and Limch1

DIOPT Version :9

• Sequence 1: NP_001027415.1
• Gene: seq / 3772396
• FlyBaseID: FBgn0028991
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: XP_036021493.1
• Gene: Limch1 / 77569
• MGIID: 1924819
• Length: 1511
• Species: Mus musculus
• Alignment Length: 836
• Identity: 161/836 - (19%)
• Similarity: 286/836 - (34%)
• Gaps: 213/836 - (25%)

  Fly   108 QQQQQQQQNVATSVADNVVTTISSSSILHTNANTNGVDTLAATQQQQQQQQQQQQQQQQQHYH-- 170
            ::.|.|:::|.|.||..|.|  .....|.||        ...|..:.:....|::.|.:...|
Mouse   499 KRNQGQREDVNTMVACTVQT--QKDEPLETN--------FRKTPDRHKDDLAQRRIQGRLTPHRE 553

  Fly   171 ---YITTTG---EDGQTPTTIVFENYNGGMPAVSSAAPTPVPVSQANAPATTTTTALVNTD---- 225
               :|..:|   .|.:|...:..........|.::.||.|       :|...|.|| :..|
Mouse   554 APSFIKLSGITEADLETWERLKVSGETRDGDAQNTCAPEP-------SPEIDTETA-IRDDFASR 610

  Fly   226 ------------------GTIIEFDGSTYEEYHVLKSEP---------GSSDCLSNGSSAVAADI 263
                              |.:.|.|..|::...:.|:.|         .|.:.:|:||....|..
Mouse   611 KARAYKKASGPRQKFVHFGPVTEIDQQTWKRLSIGKAGPRDNVEVVRHSSQNQISSGSPPSTATF 675

  Fly   264 ------------------------IKYDPQHGVVGDEEDD----DENGMLHVKYEEQSLEHDP-- 298
                                    :|..|....|.:.:::    ..|   :.|.||.:....|
Mouse   676 GLKEEQMLSPQSDCRTVPSGTDGRLKKAPWLAPVLESQEEQVCIQSN---NPKTEEVTPTQLPQD 737

  Fly   299 ---ENEHDAEQEHEY-------------------------EEYQVIKAEVEAEAAELAAGTTSYT 335
               :||...::|||.                         |...:.....|.|||.|.....
Mouse   738 GREQNEEVIQKEHEMLPRVQRPEECSGPLYGPRTPVSDDAESTSMFDMRCEEEAAVLPHSRA--- 799

  Fly   336 ISQEQTGSGNTVLSSMVPKSGSAAAAKQKRKRKTR--VIADDEQGEYLEKM-------SVRGLDI 391
             .|||....|..|.....|.....|..:.|:|...  :|..:|:.:.:||:       |.|...|
Mouse   800 -RQEQLQLINNQLREEDDKWQDDLARWKSRRRSASQDLIKKEEERKKMEKLMSGEDGTSERRKSI 863

  Fly   392 ARYEHIIDGVAYCLVCAKNDIFKTFKNKYSFQRHAYLFHEG-QNRKIFACPICNKEFSRPDKMKM 455
            ..|..|:.....    .:.::.:.:||..| |..|    || ..:.|....|......|.:..|:
Mouse   864 KTYREIVQEKER----RERELHEAYKNARS-QEEA----EGILQQYIERFTISEAVLERLEMPKI 919

  Fly   456 HKKDKHGDVPMPPSATTTPLKADGPPAKRARTARTPRVRKTKDGSTPTKKRLAQIDSVLDDVQNG 520
            .::....:    |:.::.|  .|..|.|..|           ..|.|..|..|.:::.:
Mouse   920 LERSHSTE----PNVSSFP--NDPSPMKYLR-----------QQSLPPPKFTATVETTI------ 961

  Fly   521 ESLTMAPVSVSHSQQQQQQQI--QHSITTLAPSTPSQPQHQLQTLPSLDFSGMILPGGAQLALAN 583
             :.|..|.|::.:......:|  .:::..|.|...|||::..:.|.:....|.:...| ::|
Mouse   962 -ARTSVPESIASAGTGSPSKIITPNTVPMLTPRPYSQPKNSQEVLKTFKVDGKVSMNG-EMA--- 1021

  Fly   584 PGATSSVGLQR-GPATPNGQPAPP-TTTLIYSNQLELQQALLQQQLQGQSIMIQDQAGNLVPLQL 646
            ||  ...|.:: |||.  ..|.|. |.:.::.....:..:.:|.:....||.|..:..|..|.:|
Mouse  1022 PG--DEEGKEKEGPAA--AAPGPSLTKSQMFEGVATVHDSPVQVKQGSNSIEINIKKPNSAPQEL 1082

  Fly   647 DGTQAIYTTAPQAQRQQTTATYQTTQQQQQQPAQQPAGQAQQQPHYELDNVTYLSSTAAATPTSA 711
                       .|..::|.:..|..:..:::|..........:|.:....||..|.|.|....|:
Mouse  1083 -----------TAASEETESNGQEDEDGEERPGTGDLEPDSAEPQHFTTTVTRCSPTVALVEFSS 1136

  Fly   712 E--------QQQQQQQQQHVIGTVQ---SYQILTPDGLQ-------NFQPKL-ETAELGDLCPYS 757
            .        :|.|::.:..:.|.|:   |.::..|...:       .|..|: ||.:|....|.|
Mouse  1137 NPQLKNEVPEQGQKKPEDEMSGKVELVLSQKVAKPKSPEPEATLTFPFLDKMPETNQLHLPNPSS 1201

  Fly   758 QY---TFTTHAGAQPTLNANALDAQTQ--HQQHHQQQQHHHQQQQHHQQTQLLQQQ 808
            |.   :.....|:.| ....|.|.:.:  .|:..||:|....|:::.::...|:::
Mouse  1202 QADSPSSEKSPGSTP-FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEE 1256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
seq	NP_001027415.1	C2H2 Zn finger	404..430	CDD:275370	5/25 (20%)
Limch1	XP_036021493.1	CH_LIMCH1	23..140	CDD:409127
		DUF4757	250..>311	CDD:406382
		DUF4757	<739..872	CDD:406382	29/136 (21%)
		GBP_C	<1225..1262	CDD:419202	6/32 (19%)
		LIM	1441..1498	CDD:214528

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15551
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100