DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment seq and Phf14

DIOPT Version :9

Sequence 1:	NP_001027415.1	Gene:	seq / 3772396	FlyBaseID:	FBgn0028991	Length:	882	Species:	Drosophila melanogaster
Sequence 2:	XP_006505259.1	Gene:	Phf14 / 75725	MGIID:	1923539	Length:	946	Species:	Mus musculus

Alignment Length:	353	Identity:	58/353 - (16%)
Similarity:	127/353 - (35%)	Gaps:	95/353 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KSSQGQQQQIVYVNMLPAANTLNGIPQQQQQQQYASTDGNVYQLQNEILCDANGH-AVTAATASY 97
            :||:.:|.:.:..::|.|.:             |.|:|.:.:::.:....:.:|: :...:..|.
Mouse     3 RSSKRRQVKPLAASLLEALD-------------YDSSDDSDFKVGDASDSEGSGNGSEDPSKDSG 54

  Fly    98 QTTASSPQQQ----------QQQQQQQQNVATSVADNVVTTISSSSILHTNANTNGVDTLAATQQ 152
            :.:.|..::.          |.:::|.:|....:..:....|....   .....||.......::
Mouse    55 EGSCSDSEENILEEELNEDIQVKEEQLKNSTEEIMPSDKQLIKMEK---KEEEENGERPRKKKEK 116

  Fly   153 QQQQQQQQQQQQQQQHYHYITTTGEDGQTPTTIVFENYNGGMPAVSSAAPTPVPVSQANAPATTT 217
            ::::::::::.:::............|.||.|                  :|..|:..:.|.|||
Mouse   117 EKEKEKEREKDKEKATVSDSAAASAAGTTPAT------------------SPPAVTSPSVPTTTT 163

  Fly   218 TTALVNTDGTIIE------------FDGSTYEEYHVLKSEPGSSD-------CLSNGSSAVAADI 263
            ||    |:..:.|            .|..:.||.:.:.......|       ....|.||
Mouse   164 TT----TEEQVSEPKKWNLRRNRPLLDFVSMEELNAMDDYDSEDDNDWRPTVVKRKGRSA----- 219

  Fly   264 IKYDPQHGVVGDEEDDDENGMLHVKYEEQSLEHDPENEHDAEQEHE--------YEEYQVIKAEV 320
               ..:.|..||.||||:.|         |...:.||:...:::|.        .::...:.:..
Mouse   220 ---SQKEGSDGDNEDDDDEG---------SGSEEDENDEGNDEDHSSPASEAGGKKKRSKVLSRN 272

  Fly   321 EAEAAELAAGTTSYTISQEQTGSGNTVL 348
            .|:..||.  ..|.|:||.::...:.:|
Mouse   273 SADDEELT--NDSLTLSQSKSNEDSLIL 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
seq	NP_001027415.1	C2H2 Zn finger	404..430	CDD:275370
Phf14	XP_006505259.1	PHD1_PHF14	314..370	CDD:277036
		ePHD_PHF14	378..491	CDD:277144
		PHD2_PHF14	720..769	CDD:277037
		PHD3_PHF14	863..911	CDD:277038
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900