Protein Alignment seq and kdm4c

DIOPT Version :10

• Sequence 1: NP_001027415.1
• Gene: seq / 3772396
• FlyBaseID: FBgn0028991
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_001077320.1
• Gene: kdm4c / 570194
• ZFINID: ZDB-GENE-070209-38
• Length: 1482
• Species: Danio rerio
• Alignment Length: 885
• Identity: 151/885 - (17%)
• Similarity: 279/885 - (31%)
• Gaps: 278/885 - (31%)

  Fly    99 TTASSPQ-QQQQQQQQQQNVATSV-----ADNVVTTISSSSILHTNANTNGVDTLAATQQQQQQQ 157
            |.:::|: |...|:::::..:||:     ....:.|:.|:.:..:...:.   :.|.|.:.::::
Zfish   349 TPSTTPELQSWLQRRRRKTPSTSLHAPRSCSKRLKTVDSAPVKGSGRRSR---SAALTAKNKEEE 410

  Fly   158 QQQQQQQQQQHYHYITTTGEDGQTPTTIVFENYNGGMPAVSS-----------AAPTPVPVSQAN 211
            ::...:.|::..:.....|..|:....:........:.|.|:           ..||....|..|
Zfish   411 EEDPVKHQKESQYSSELKGLAGRQMCVVKVTRVESDLLAQSTRQVKEASPERLLTPTLTTTSSQN 475

  Fly   212 AP---ATTTTTALVNTDGTIIEFDGSTYEEYHVLKSEPGSSDCLSNGSSAVAADIIKYDPQHGVV 273
            .|   .|::.|:|:..:|.:.:...||      .:|||.|:     ..|.:..|:        .:
Zfish   476 DPDVGHTSSQTSLILDEGQVSKNTNST------AQSEPEST-----SESDIIVDV--------TL 521

  Fly   274 GDEEDDDENGMLHVKYEEQSLEHDPENEHDAEQEHEYEEYQVIKAEVEAEAAELAAGTTSYTISQ 338
            |.|..        .|...|:|..:                         ...|..|.:...|.|.
Zfish   522 GSERT--------AKNPNQTLNCE-------------------------SVLETIAPSIPVTHSL 553

  Fly   339 EQTGSGNTVLSSMVPKSGSAAAAKQKRKRKTRVIADDE-----QGEYLEKMSVRGLDIARYEHII 398
            ....:|.|||.|   :|.|..|..:..:.....:.:|.     ...|.|:.|: .||.|     :
Zfish   554 TLHSTGATVLFS---ESDSQQAKIETEETVIDTLTEDSIDCGTSALYKEQSSI-SLDPA-----L 609

  Fly   399 DGVAYCLVCAKNDIFKTFKNKYSFQRHAYLFHEGQNRKIFACPICNKEFSRPDKMKMHKKDKHGD 463
            .|                 ::.|..|        .|.:|...|.|......|:.:: .:.:....
Zfish   610 QG-----------------SEPSMNR--------TNSEIQTTPFCEMPLLMPELIE-ERVNPQCL 648

  Fly   464 VPMPPSAT--------------TTPL----KADGPPAKRARTARTPRVRKTKDGSTP------TK 504
            .|..||.|              :.|:    |:..||      ..|..||...:.:.|      .|
Zfish   649 APEMPSLTLAIRPDSANHQPYNSAPILHLEKSHSPP------VITDEVRGCSERACPDWPFILPK 707

  Fly   505 KRLAQIDSVLDDVQNGESLTMAPVSVS-----------------HSQQQQQQQIQH-SITTLAPS 551
            :.::|....:.|     |....|.|.|                 |......|..|| ||:..  :
Zfish   708 EGVSQSHKSISD-----SFKAKPTSASFAPQWGTPEESKQEGNIHKCTSTDQNTQHESISNC--T 765

  Fly   552 TPSQPQHQLQTLPSLDF--SGMILPGGAQLALANPGATSSVGLQRGPATPNGQPAPPTTTLIYSN 614
            ||::...|......:||  |.|:...|.:.:......:||:...:.    |...:.|.|  |:.|
Zfish   766 TPTRSILQSSATTHMDFIDSKMVEGVGKETSQRIEEQSSSLTSSQS----NFAESKPFT--IWKN 824

  Fly   615 QLELQQALLQQQLQGQSIM--------------IQDQAG--------------------NL--VP 643
            ......|:|.:.||.:.::              :..::|                    ||  :|
Zfish   825 LSSDNPAVLIESLQPELVVGLTADYAHDSLPYTMWSESGCQQEKFSDSPNSSPHTQTWTNLEPIP 889

  Fly   644 LQLDGTQAIYTTAPQAQRQQTTATYQTTQQQQQQPA------QQPAGQAQQQPHYEL-------- 694
            :|...|: :...||...:|         :.::.:||      :|...|..|:..:::
Zfish   890 MQCSDTE-VSENAPLDLKQ---------ENEEVEPAEACELNEQAGSQEPQEREFKIQEYYRSVK 944

  Fly   695 --------DNVTYLSSTAAATPTSAEQQQQQQQQQHVIGTVQSYQILTPDGLQNFQPKLETAELG 751
                    |:.:..|....|..:|...::........:.|          ||          |.|
Zfish   945 SEHDGSVSDSDSCESGDKGADSSSESSEENPMSDPEYVET----------GL----------EPG 989

  Fly   752 DLCPYSQYTFT------THAGAQPTLNANALDAQTQHQQHHQQQQHHHQQQQHHQQTQLLQQQPF 810
            ::|.|...|..      .|...:||  |.|:.:..:.|.....:.......:..:.......:|.
Zfish   990 EVCTYHMQTVKKTAKSWRHPLRKPT--ARAVPSAVKQQAASDDEVIEECASEEDEPETEEWAKPL 1052

  Fly   811 A---THHNPHQQFMELKNELLIKGGDAYTLDTASM-YHLP 846
            .   .|...|.|:.:..|....|......:.|..| ||.|
Zfish  1053 VHLWQHRKAHFQYEQEYNMTAAKNAPHCAVCTLFMPYHQP 1092

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
seq	NP_001027415.1	C2H2 Zn finger	404..430	CDD:275370	2/25 (8%)
kdm4c	NP_001077320.1	JmjN	16..57	CDD:128818
		JmjC	177..293	CDD:396791
		PHD_SF	1079..1176	CDD:473978	5/14 (36%)
		ePHD_JMJD2C	1185..1294	CDD:277185
		Tudor_JMJD2C_rpt1	1310..1363	CDD:410536
		Tudor_JMJD2C_rpt2	1367..1426	CDD:410539