Protein Alignment CG32270 and KLK1

DIOPT Version :10

• Sequence 1: NP_728837.1
• Gene: CG32270 / 3772375
• FlyBaseID: FBgn0052270
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 79/246 - (32%)
• Similarity: 119/246 - (48%)
• Gaps: 29/246 - (11%)

  Fly    30 RIVGGHPSDVWHQPHMVNIRRRGNFECGGSLVTPRCVLTAAHCLNDGNPSDFVVRGGVTYLSDMR 94
            |||||...:...||....:.....|:|||.||..:.|||||||::|    ::.:..|...|.|..
Human    24 RIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISD----NYQLWLGRHNLFDDE 84

  Fly    95 NSR---YVRKILMPSAYSRTTLD-----------HDVALLQLKQPLQ--ASIAKPISLAVRSPRP 143
            |:.   :|.:......::.:.|:           ||:.||:|.:|..  ....|.:.|....|..
Human    85 NTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPTEEPEV 149

  Fly   144 GSFVRVSGWGLTDSSSTSLPNQLQSVHVQVMPQRECRDLYRGYRNITSSMFCAS-VPGLKDACAG 207
            ||....||||..:..:.|.|:.||.|.::::|..||:..:  .:.:|..|.|.. :.|.||.|.|
Human   150 GSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAH--VQKVTDFMLCVGHLEGGKDTCVG 212

  Fly   208 DSGGPVVNSNGILVGVVSWGRAHRCAARDSPG----VYSDVSYLSDWIADN 254
            |||||:: .:|:|.||.|||.. .|...:.|.    |.|.|.::.|.||:|
Human   213 DSGGPLM-CDGVLQGVTSWGYV-PCGTPNKPSVAVRVLSYVKWIEDTIAEN 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32270	NP_728837.1	Tryp_SPc	30..251	CDD:214473	76/241 (32%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	74/239 (31%)