DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32270 and PRSS36

DIOPT Version :9

Sequence 1:	NP_728837.1	Gene:	CG32270 / 3772375	FlyBaseID:	FBgn0052270	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_775773.2	Gene:	PRSS36 / 146547	HGNCID:	26906	Length:	855	Species:	Homo sapiens

Alignment Length:	292	Identity:	96/292 - (32%)
Similarity:	143/292 - (48%)	Gaps:	46/292 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 MLLPLMFWMLWI--------------RESVAEELELRR---SPRIVGGHPSDVWHQPHMVNIRRR 51
            :||||:  ||.|              .:...|:|:..|   |.|||||..:.....|..|::...
Human     5 LLLPLV--MLVISPIPGAFQDSALSPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHG 67

  Fly    52 GNFECGGSLVTPRCVLTAAHC-LNDGN---PSDFVVRGGVTYLS---DMRNSRYVRKILMPSAYS 109
            |...|||||:.|..||:|||| :.:|.   .:::.|..||....   |..::|.|..|::|:.||
Human    68 GGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYS 132

  Fly   110 RTTLDHDVALLQLKQPLQASIAK---PISLAVRSPR--PGSFVRVSGWG-LTDSSSTSLPNQLQS 168
            :..|..|:|||:|..|  ||:..   |:.|...|.|  .|:....:||| :.::....||..||.
Human   133 QVELGADLALLRLASP--ASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQE 195

  Fly   169 VHVQVMPQRECRDLYR--GYRNIT----SSMFCASVP-GLKDACAGDSGGPVVNSNG---ILVGV 223
            |.::::.:..|:.||.  |..|:|    ..|.||..| |.:|.|.||||||:|...|   ...|:
Human   196 VELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGI 260

  Fly   224 VSWGRAHRCAARDSPGVYSDVSYLSDWIADNI 255
            .|:|  ..|..|:.|||::.|:....||.:.:
Human   261 TSFG--FGCGRRNRPGVFTAVATYEAWIREQV 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32270	NP_728837.1	Tryp_SPc	30..251	CDD:214473	83/243 (34%)
CG32270	NP_728837.1	Tryp_SPc	31..254	CDD:238113	84/245 (34%)
PRSS36	NP_775773.2	Tryp_SPc	46..286	CDD:214473	83/243 (34%)
		Tryp_SPc	47..289	CDD:238113	84/245 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..316
		Tryp_SPc	330..538	CDD:304450
		Tryp_SPc	601..783	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100