DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32270 and f12

DIOPT Version :9

Sequence 1:	NP_728837.1	Gene:	CG32270 / 3772375	FlyBaseID:	FBgn0052270	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	XP_017947702.2	Gene:	f12 / 100493769	XenbaseID:	XB-GENE-1004811	Length:	597	Species:	Xenopus tropicalis

Alignment Length:	257	Identity:	85/257 - (33%)
Similarity:	120/257 - (46%)	Gaps:	47/257 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 PRIVGGHPSDVWHQPHMVNIRRRGNFECGGSLVTPRCVLTAAHCLNDGNPSDFVVRGGVTYLS-D 92
            ||||||..:.....|::..:....:| |||||::|..::||||||:.        |..||.:| .
Frog   357 PRIVGGLVALPASHPYIAALYIDNHF-CGGSLISPCWIVTAAHCLDQ--------RPNVTKISVV 412

  Fly    93 MRNSRY-----------VRKILMPSAYSRTTLDHDVALLQLK--QPLQAS----IAKPISLAVRS 140
            :..||:           |.|.::...|...||.||:||:::|  ..|.||    ..:||.|
Frog   413 LGQSRFNTTDQHTVTLLVEKYILHEKYYGDTLQHDIALVKVKSINGLCASEFSQFVQPICL---- 473

  Fly   141 PRPGSFVR--------VSGWGLTDSSSTSLPNQLQSVHVQVMPQRECRDLYRGYRNITSSMFCAS 197
              |..|..        |:|||.....:......||...:.::|..:|:........:...|.||.
Frog   474 --PQQFKMAESTKQCVVAGWGHQYEGAEHYAFFLQEASMPIIPYTQCQSPSVHGDRMLPGMLCAG 536

  Fly   198 -VPGLKDACAGDSGGPV---VNSNGILVGVVSWGRAHRCAARDSPGVYSDVSYLSDWIADNI 255
             :.|..|||.||||||:   |:....|.||||||..  ||..:.||||:.|:..:|||..||
Frog   537 FMEGGVDACQGDSGGPLVCEVDGRIELHGVVSWGSG--CAEENKPGVYTAVTSYTDWIRANI 596

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32270	NP_728837.1	Tryp_SPc	30..251	CDD:214473	80/250 (32%)
CG32270	NP_728837.1	Tryp_SPc	31..254	CDD:238113	81/252 (32%)
f12	XP_017947702.2	fn2	46..87	CDD:394995
		EGF_CA	95..129	CDD:238011
		KR	213..298	CDD:214527
		Tryp_SPc	359..595	CDD:238113	81/252 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910