Protein Alignment Tyler and MME1

DIOPT Version :10

• Sequence 1: NP_608327.2
• Gene: Tyler / 3772349
• FlyBaseID: FBgn0031038
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_013889.1
• Gene: MME1 / 855202
• SGDID: S000004776
• Length: 368
• Species: Saccharomyces cerevisiae
• Alignment Length: 401
• Identity: 86/401 - (21%)
• Similarity: 146/401 - (36%)
• Gaps: 132/401 - (32%)

  Fly    49 VVSALVGGLITTFVVTPLEVVKTRVQTQHAIRQRPTVSKLCYVYHNGLMTHVCRSSDICVPKPGR 113
            |||..:||.|....:..|:.||||.|
Yeast    57 VVSGGIGGKIGDSAMHSLDTVKTRQQ--------------------------------------- 82

  Fly   114 DPQNLRPLRGAMDAFVKIVCTSGF-SGLWAGLSPTLVSALPSTIIYFLTYEYIKNSLSHIYLVSQ 177
            ...|::..|..:.|:..|....|. .||:.|....::.:.||..|:|.||||.|.::
Yeast    83 GAPNVKKYRNMISAYRTIWLEEGVRRGLYGGYMAAMLGSFPSAAIFFGTYEYTKRTM-------- 139

  Fly   178 KFEESGMKDQVPGADGGDPLDQATRGINVSATAPVSTASLPYYVPMASGICSRTIVVTAITPIEM 242
             .|:..:.|.:.....|      ..|..:|:..         |||               :.:..
Yeast   140 -IEDWQINDTITHLSAG------FLGDFISSFV---------YVP---------------SEVLK 173

  Fly   243 VRIKMQSEY--------MTYAELWRVLRSLIRQHGILGLWRGWPPTVMRDAPFSGTYWAVYEAIK 299
            .|:::|..:        ..|:.|...::::|::.|...|:.|:..|:.||.|||...:|.||..:
Yeast   174 TRLQLQGRFNNPFFQSGYNYSNLRNAIKTVIKEEGFRSLFFGYKATLARDLPFSALQFAFYEKFR 238

  Fly   300 R-AFSVT-------EPTFLFSFLTGAISGAVATFVTMPFDLITTHTQIELGQDVLYEEIGAGTGA 356
            : ||.:.       |.:.....||||.:|.:|..:|.|.|::.|..|.:
Yeast   239 QLAFKIEQKDGRDGELSIPNEILTGACAGGLAGIITTPMDVVKTRVQTQ---------------- 287

  Fly   357 GTGTGAGARPKTPQSA--------VANSRPSVLSR-----MRQIYRLQGVRGLYVGVMPRMLRVV 408
                    :|.:..:.        |.|.||:.||.     :|.:|:.:||.|.:.||.||.:...
Yeast   288 --------QPPSQSNKSYSVTHPHVTNGRPAALSNSISLSLRTVYQSEGVLGFFSGVGPRFVWTS 344

  Fly   409 PACAIMISTFE 419
            ...:||:..::
Yeast   345 VQSSIMLLLYQ 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tyler	NP_608327.2	Mito_carr	41..171	CDD:395101	29/122 (24%)
		Mito_carr	216..303	CDD:395101	21/95 (22%)
		Mito_carr	306..429	CDD:395101	30/127 (24%)
MME1	NP_013889.1	Mito_carr	51..142	CDD:395101	29/132 (22%)
		PTZ00168	55..>283	CDD:185494	66/303 (22%)
		Mito_carr	252..363	CDD:395101	30/128 (23%)