Protein Alignment Tyler and MTM1

DIOPT Version :9

• Sequence 1: NP_608327.2
• Gene: Tyler / 3772349
• FlyBaseID: FBgn0031038
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_011773.3
• Gene: MTM1 / 853173
• SGDID: S000003489
• Length: 366
• Species: Saccharomyces cerevisiae
• Alignment Length: 439
• Identity: 108/439 - (24%)
• Similarity: 182/439 - (41%)
• Gaps: 152/439 - (34%)

  Fly    47 QQVVSALVGGLITTFVVTPLEVVKTRVQTQHAI--------RQRPTV----SKLCYVYHNGLMTH 99
            ::::||..|.::|:.::||::||:.|:|.|..|        .:.|..    ||:      ...|:
Yeast    14 ERMLSAGAGSVLTSLILTPMDVVRIRLQQQQMIPDCSCDGAAEVPNAVSSGSKM------KTFTN 72

  Fly   100 V---------------------CRSSDICVPKPGRDPQNLRPLRGAMDAFVKIVCTSGFSGLWAG 143
            |                     |::|.:             ...|.::||.||....|.:.||.|
Yeast    73 VGGQNLNNAKIFWESACFQELHCKNSSL-------------KFNGTLEAFTKIASVEGITSLWRG 124

  Fly   144 LSPTLVSALPSTIIYFLTYEYIKNSLSHIYLVSQKFEESGMKDQVPGADGGDPLDQATRGINVSA 208
            :|.||:.|:|:.::||..||||::
Yeast   125 ISLTLLMAIPANMVYFSGYEYIRD----------------------------------------- 148

  Fly   209 TAPVSTASLPYYVPMASGICSRTIVVTAITPIEMVRIKMQS--EYMTYAELWRVLRSLI----RQ 267
            .:|:: ::.|...|:..|..:|....|:|.|:|:|:.|:||  ......:.|.:::.|:    ::
Yeast   149 VSPIA-STYPTLNPLFCGAIARVFAATSIAPLELVKTKLQSIPRSSKSTKTWMMVKDLLNETRQE 212

  Fly   268 HGILG----LWRGWPPTVMRDAPFSGTYWAVYEAIKR-------AFSVTEPT---FLFSFLTGAI 318
            ..::|    |::|...|:.||.|||..||:.||..|.       .|:..:..   |:.||.:|.|
Yeast   213 MKMVGPSRALFKGLEITLWRDVPFSAIYWSSYELCKERLWLDSTRFASKDANWVHFINSFASGCI 277

  Fly   319 SGAVATFVTMPFDLITTHTQIELGQDVLYEEIGAGTGAGTGTGAGARPKTPQSAVANSRPSVLSR 383
            ||.:|...|.|||:..|..||                               |.:.||.|...:|
Yeast   278 SGMIAAICTHPFDVGKTRWQI-------------------------------SMMNNSDPKGGNR 311

  Fly   384 MRQ-------IYRLQGVRGLYVGVMPRMLRVVPACAIMISTFEYSKSFF 425
            .|.       |:|.:|:..||.|:..|::::.|:||||||::|.||..|
Yeast   312 SRNMFKFLETIWRTEGLAALYTGLAARVIKIRPSCAIMISSYEISKKVF 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tyler	NP_608327.2	Mito_carr	41..171	CDD:278578	39/156 (25%)
		Mito_carr	216..302	CDD:278578	28/102 (27%)
		Mito_carr	306..429	CDD:278578	39/130 (30%)
MTM1	NP_011773.3	Mito_carr	14..149	CDD:278578	39/194 (20%)
		Mito_carr	154..255	CDD:278578	28/100 (28%)
		Mito_carr	264..364	CDD:278578	39/128 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341333
Domainoid	1	1.000	71	1.000	Domainoid score	I2242
eggNOG	1	0.900	-	-		E1_KOG0761
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1011
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53824
OrthoFinder	1	1.000	-	-		FOG0001594
OrthoInspector	1	1.000	-	-		otm46805
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45760
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1001
TreeFam	1	0.960	-	-
	12	11.860