Protein Alignment Tyler and SLC25A38

DIOPT Version :10

• Sequence 1: NP_608327.2
• Gene: Tyler / 3772349
• FlyBaseID: FBgn0031038
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_060345.2
• Gene: SLC25A38 / 54977
• HGNCID: 26054
• Length: 304
• Species: Homo sapiens
• Alignment Length: 386
• Identity: 87/386 - (22%)
• Similarity: 144/386 - (37%)
• Gaps: 127/386 - (32%)

  Fly    46 MQQVVSAL----VGGLITTFVVTPLEVVKTRVQT----QHAIRQRPTVSKLCYVYHNGLMTHVCR 102
            :..|:.|.    :.|..:|.:..||:::|||:||    .|..|:
Human    24 LHPVIKAFLCGSISGTCSTLLFQPLDLLKTRLQTLQPSDHGSRR--------------------- 67

  Fly   103 SSDICVPKPGRDPQNLRPLRGAMDAFVKIVCTSGFSGLWAGLSPTLVSALPSTIIYFLTYEYIKN 167
                               .|.:...:|:|.|....|||.|:||::|..:|...|||.|
Human    68 -------------------VGMLAVLLKVVRTESLLGLWKGMSPSIVRCVPGVGIYFGT------ 107

  Fly   168 SLSHIYLVSQKFEESGMKDQVPGADGGDPLDQATRGINVSATAPVSTASLPYYVPMASGICSRTI 232
                :|.:.|.|..            |.|              |.:..|      :..|:.||::
Human   108 ----LYSLKQYFLR------------GHP--------------PTALES------VMLGVGSRSV 136

  Fly   233 VVTAITPIEMVRIKMQSEYMTYAELWRVLRSLIRQHGILGLWRGWPPTVMRDAPFSGTYWAVYEA 297
            ....::||.:::.:.:|....|..::..|||:....|..||:.|...|::|||||||.|...|..
Human   137 AGVCMSPITVIKTRYESGKYGYESIYAALRSIYHSEGHRGLFSGLTATLLRDAPFSGIYLMFYNQ 201

  Fly   298 IKR--AFSVTEPTF--LFSFLTGAISGAVATFVTMPFDLITTHTQIELGQDVLYEEIGAGTGAGT 358
            .|.  .....:.|.  :.:|..|..:|.:|:.||.|.|:|.||.|:   ..:.::.||
Human   202 TKNIVPHDQVDATLIPITNFSCGIFAGILASLVTQPADVIKTHMQL---YPLKFQWIG------- 256

  Fly   359 GTGAGARPKTPQSAVANSRPSVLSRMRQIYRLQGVRGLYVGVMPRMLRVVPACAIMISTFE 419
                                   ..:..|::..|:||.:.|.:||.||.....|:..:.:|
Human   257 -----------------------QAVTLIFKDYGLRGFFQGGIPRALRRTLMAAMAWTVYE 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tyler	NP_608327.2	Mito_carr	41..171	CDD:395101	29/132 (22%)
		Mito_carr	216..303	CDD:395101	26/88 (30%)
		Mito_carr	306..429	CDD:395101	26/116 (22%)
SLC25A38	NP_060345.2	Solcar 1. /evidence=ECO:0000255|HAMAP-Rule:MF_03064	25..114		30/138 (22%)
		Mito_carr	26..117	CDD:395101	32/140 (23%)
		Mito_carr	120..209	CDD:395101	28/108 (26%)
		Solcar 2. /evidence=ECO:0000255|HAMAP-Rule:MF_03064	121..205		27/89 (30%)
		Solcar 3. /evidence=ECO:0000255|HAMAP-Rule:MF_03064	215..299		25/113 (22%)
		Mito_carr	217..304	CDD:395101	25/111 (23%)