DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10731 and dmac2l

DIOPT Version :9

Sequence 1:	NP_001027422.1	Gene:	CG10731 / 3772305	FlyBaseID:	FBgn0034081	Length:	203	Species:	Drosophila melanogaster
Sequence 2:	NP_001017243.1	Gene:	dmac2l / 549997	XenbaseID:	XB-GENE-978777	Length:	199	Species:	Xenopus tropicalis

Alignment Length:	174	Identity:	53/174 - (30%)
Similarity:	96/174 - (55%)	Gaps:	5/174 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 RGIWGYVAVAFNQVDAERLSKVGANRLCAEWIIKNGGGVRFVESPSRLWKDYNSLP-GENTQFCI 85
            |..||::...||:||.||:...|.:|..:||:::.|..||: :...|..:|||.|| |...:|.|
Frog    23 RYFWGWLNAVFNKVDYERIKDFGPDRAASEWLLRCGAHVRY-KGFERWQQDYNGLPTGPLGKFKI 86

  Fly    86 KVVDASNSSIMKIGLEHLKDCRSIDTVIFHNCKHLENDGLE---GLHHISSSLQRLQVSGCYNIT 147
            :.::|::|.||..|.:||.....::.:....|.::|:..||   .:.::.:||:||::..|.|:|
Frog    87 QAINATDSCIMYRGFDHLDGLEHVEEIKLCKCIYIEDTCLERMSKIENLQNSLRRLEIISCGNVT 151

  Fly   148 DSGLAVIGELKNLRQLLIFDMIFVKNMEAVAASLKKQLPSCDIK 191
            |.|:..:..|:||..|.:.|:..:...:.....|:...||..::
Frog   152 DRGIIALNTLRNLEYLFLSDLPGITKKQTTVEMLQTANPSLHVE 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10731	NP_001027422.1	AMN1	<91..167	CDD:187754	23/78 (29%)
		leucine-rich repeat	109..134	CDD:275381	4/27 (15%)
		leucine-rich repeat	135..159	CDD:275381	9/23 (39%)
dmac2l	NP_001017243.1	leucine-rich repeat	110..137	CDD:275381	4/26 (15%)
		LRR_CC	138..158	CDD:197685	9/19 (47%)
		leucine-rich repeat	139..163	CDD:275381	9/23 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	99	1.000	Domainoid score	I7037
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H12232
Inparanoid	1	1.050	99	1.000	Inparanoid score	I4881
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1395428at2759
OrthoFinder	1	1.000	-	-		FOG0007106
OrthoInspector	1	1.000	-	-		oto103178
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4273
SonicParanoid	1	1.000	-	-		X5196
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090