DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10731 and dmac2l

DIOPT Version :9

Sequence 1:	NP_001027422.1	Gene:	CG10731 / 3772305	FlyBaseID:	FBgn0034081	Length:	203	Species:	Drosophila melanogaster
Sequence 2:	NP_956512.1	Gene:	dmac2l / 393187	ZFINID:	ZDB-GENE-040426-959	Length:	199	Species:	Danio rerio

Alignment Length:	175	Identity:	58/175 - (33%)
Similarity:	96/175 - (54%)	Gaps:	5/175 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 QRGIWGYVAVAFNQVDAERLSKVGANRLCAEWIIKNGGGVRFVESPSRLWKDYNSLP-GENTQFC 84
            :|..||::...||:||.||:..||.:|..|||:::.|..||| ....|...|||.|| |...::.
Zfish    22 RREFWGWLNAVFNKVDYERIKAVGPDRAAAEWLLRCGAKVRF-RGFDRWQHDYNGLPTGPLGRYR 85

  Fly    85 IKVVDASNSSIMKIGLEHLKDCRSIDTVIFHNCKHLENDGLEGLHHISS---SLQRLQVSGCYNI 146
            |:.:||:.|.||..|.:||:....::.:..:.|.::|:..||.|..|.:   :::::.|..|.|:
Zfish    86 IEAIDATESCIMYRGFDHLEGLEHVEEIRLNKCIYIEDACLERLGQIKTLQDTVKQMTVVSCGNV 150

  Fly   147 TDSGLAVIGELKNLRQLLIFDMIFVKNMEAVAASLKKQLPSCDIK 191
            ||.||..:..|..|.:|.:.|:..||:.:.....|:..||...|:
Zfish   151 TDKGLIALHHLGKLERLFLSDLPGVKDKDQTVDRLQAALPRLTIE 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10731	NP_001027422.1	AMN1	<91..167	CDD:187754	22/78 (28%)
		leucine-rich repeat	109..134	CDD:275381	6/27 (22%)
		leucine-rich repeat	135..159	CDD:275381	8/23 (35%)
dmac2l	NP_956512.1	leucine-rich repeat	111..129	CDD:275381	4/17 (24%)
dmac2l	NP_956512.1	leucine-rich repeat	132..163	CDD:275381	9/30 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574771
Domainoid	1	1.000	100	1.000	Domainoid score	I6949
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12232
Inparanoid	1	1.050	101	1.000	Inparanoid score	I4981
OMA	1	1.010	-	-		QHG45531
OrthoDB	1	1.010	-	-		D1395428at2759
OrthoFinder	1	1.000	-	-		FOG0007106
OrthoInspector	1	1.000	-	-		oto40174
orthoMCL	1	0.900	-	-		OOG6_107545
Panther	1	1.100	-	-	LDO	PTHR13382
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5196
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.910