DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10731 and C05C8.1

DIOPT Version :9

Sequence 1:	NP_001027422.1	Gene:	CG10731 / 3772305	FlyBaseID:	FBgn0034081	Length:	203	Species:	Drosophila melanogaster
Sequence 2:	NP_504842.1	Gene:	C05C8.1 / 179119	WormBaseID:	WBGene00015460	Length:	200	Species:	Caenorhabditis elegans

Alignment Length:	195	Identity:	59/195 - (30%)
Similarity:	96/195 - (49%)	Gaps:	18/195 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 RITQLLARDPKDQRGIWG--YVAVAFNQVDAERLSKVGANRLCAEWIIKNGGGVRFVESPSRLWK 71
            :.||.|.     |..|.|  :|...||..|.:|:.:|||:|..||||::.||.::| ...:..::
Worm     9 KFTQALG-----QHNIPGLRWVLEGFNNYDVQRVKEVGADRAAAEWIVRCGGSIKF-NQIAETFE 67

  Fly    72 DYNSLPGENTQF---------CIKVVDASNSSIMKIGLEHLKDCRSIDTVIFHNCKHLENDGLEG 127
            |||.|.....|.         .::.:.|.|:|:...|..|.:....|.:|.|..||:|.:.|||.
Worm    68 DYNCLVKRTAQLDPRLSQDNVTLETIRAVNASVTGFGCRHFEGLTGIKSVYFIKCKNLHDFGLEY 132

  Fly   128 L-HHISSSLQRLQVSGCYNITDSGLAVIGELKNLRQLLIFDMIFVKNMEAVAASLKKQLPSCDIK 191
            : :|:...|:.|.:..|..||:.||..:.:...|.:|::.::..|...|.|...|:..||..||:
Worm   133 MGNHVGGHLKTLHIEECRRITEFGLEHLTKFSALDKLVLRNLKSVHGKEKVQEKLRGALPKTDIQ 197

Fly 192 191
Worm 198 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10731	NP_001027422.1	AMN1	<91..167	CDD:187754	23/76 (30%)
		leucine-rich repeat	109..134	CDD:275381	10/25 (40%)
		leucine-rich repeat	135..159	CDD:275381	7/23 (30%)
C05C8.1	NP_504842.1	leucine-rich repeat	90..113	CDD:275381	5/22 (23%)
C05C8.1	NP_504842.1	leucine-rich repeat	141..165	CDD:275381	7/23 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156659
Domainoid	1	1.000	89	1.000	Domainoid score	I4956
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I3683
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45531
OrthoDB	1	1.010	-	-		D1395428at2759
OrthoFinder	1	1.000	-	-		FOG0007106
OrthoInspector	1	1.000	-	-		oto17539
orthoMCL	1	0.900	-	-		OOG6_107545
Panther	1	1.100	-	-	LDO	PTHR13382
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4273
SonicParanoid	1	1.000	-	-		X5196
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.940