DRSC/TRiP Functional Genomics Resources

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Protein Alignment fabp and FABP4

DIOPT Version :9

Sequence 1:NP_001027179.1 Gene:fabp / 3772232 FlyBaseID:FBgn0037913 Length:157 Species:Drosophila melanogaster
Sequence 2:NP_001433.1 Gene:FABP4 / 2167 HGNCID:3559 Length:132 Species:Homo sapiens


Alignment Length:113 Identity:59/113 - (52%)
Similarity:75/113 - (66%) Gaps:2/113 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 SFVGKKYKLDKSENFDEYMKELGVGLVTRKMGNSLSPTVEVTLEGDTYTLTTTSTFKTSAISFKL 66
            :||| .:||..|||||:||||:|||..|||:.....|.:.:::.||..|:.:.||||.:.|||.|
Human     4 AFVG-TWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFIL 67

  Fly    67 GVEFDEETLDGRNVKSIITLDGNKLTQEQKGD-KPTTIVREFTDNELI 113
            |.||||.|.|.|.|||.|||||..|...||.| |.|||.|:..|::|:
Human    68 GQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLV 115

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fabpNP_001027179.1 Lipocalin 7..>107 CDD:278490 54/100 (54%)
FABP4NP_001433.1 FABP4 2..131 CDD:381242 59/113 (52%)
Nuclear localization signal. /evidence=ECO:0000250 22..32 6/9 (67%)
Fatty acid binding 127..129
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165156806
Domainoid 1 1.000 115 1.000 Domainoid score I6016
eggNOG 1 0.900 - - E1_KOG4015
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 119 1.000 Inparanoid score I4779
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG45877
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000407
OrthoInspector 1 1.000 - - otm40966
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11955
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R5175
SonicParanoid 1 1.000 - - X240
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1312.890

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