Protein Alignment sea and SLC25A21

DIOPT Version :10

• Sequence 1: NP_001027175.1
• Gene: sea / 3772221
• FlyBaseID: FBgn0037912
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_085134.1
• Gene: SLC25A21 / 89874
• HGNCID: 14411
• Length: 299
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 91/301 - (30%)
• Similarity: 138/301 - (45%)
• Gaps: 39/301 - (12%)

  Fly    37 IVAGGITGGIEICITYPTEYVKTQLQLDEKGA-AKKYNGIFDCVKKTVGERGFLGLYRGLSVLVY 100
            |||||..|.:|||:.:|.:.|||:.|:..... ...|..:.|..:......|..|.|:|:...:.
Human    17 IVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKGILPPIL 81

  Fly   101 GSIPKSAARFGAFEFLKSNAVDSRGQLSNSGKL---LCGLGAGVCEAIVAVTPMETIKVKFINDQ 162
            ...||.|.:|..||..|.    ..|.:|.|..|   :.|||:|:.|||| |.|.|.:||..   |
Human    82 AETPKRAVKFFTFEQYKK----LLGYVSLSPALTFAIAGLGSGLTEAIV-VNPFEVVKVGL---Q 138

  Fly   163 RSGN-----PKFRGFAHGVGQIIKSE--GISGIYKGLTPTILKQGSNQAIRFFVLESLKDLYKGD 220
            .:.|     |...|:|.   ||||.|  |:.|:.||||.|:.:.|....:.|....::|::.
Human   139 ANRNTFAEQPSTVGYAR---QIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMI--- 197

  Fly   221 DHTKPVPKLVVGVF------GAIAGAASVFGNTPLDVVKTRMQGLE----ASKYKNTAHCAVEIL 275
                ||.|..:..|      |.::|..:...|.|.||.|:|:||.:    ..||:........:.
Human   198 ----PVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVY 258

  Fly   276 KNEGPAAFYKGTVPRLGRVCLDVAITFMIYDSFMDLFNKVW 316
            :.||..|.|||.:|::.|:....|:..::|:.......:.|
Human   259 QEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYSWLQENW 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sea	NP_001027175.1	Mito_carr	34..117	CDD:395101	26/80 (33%)
		Mito_carr	125..220	CDD:395101	37/104 (36%)
		Mito_carr	235..314	CDD:395101	22/82 (27%)
SLC25A21	NP_085134.1	Solcar 1	11..100		27/86 (31%)
		Mito_carr	15..105	CDD:395101	28/91 (31%)
		Mito_carr	105..197	CDD:395101	36/98 (37%)
		Solcar 2	107..196		35/95 (37%)
		Mito_carr	205..298	CDD:395101	23/92 (25%)
		Solcar 3	205..294		23/88 (26%)