Protein Alignment sea and SLC25A22

DIOPT Version :10

• Sequence 1: NP_001027175.1
• Gene: sea / 3772221
• FlyBaseID: FBgn0037912
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001412263.1
• Gene: SLC25A22 / 79751
• HGNCID: 19954
• Length: 348
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 96/322 - (29%)
• Similarity: 141/322 - (43%)
• Gaps: 72/322 - (22%)

  Fly    31 QVGLKG-IVAGGITGGIEICITYPTEYVKTQLQLDEKGAAKKYNGI------------------- 75
            |:.|.. ::.|||.|.|.:...:|.:..||:||..:.| .:.|..|
Human     5 QISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNG-QRVYTSIPRQSRDPGLRLAPAGPGSP 68

  Fly    76 ------FDCVKKTVGERGFLGLYRGLSVLVYGSIPKSAARFGAFEFLKSNAVDSRGQLSNSG--- 131
                  .||:.|||...|:.|:|||.:|.:....|:.|.:..|.:|.       |.|||..|
Human    69 CPLGHRSDCLIKTVRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFF-------RHQLSKDGQKL 126

  Fly   132 ----KLLCGLGAGVCEAIVAVTPMETIKVKF-----INDQR-----SGNPKFRGFAHG------- 175
                ::|.|.|||.|:.|| .||||.:|::.     |..||     .|....:|.|..
Human   127 TLLKEMLAGCGAGTCQVIV-TTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAA 190

  Fly   176 --------VGQIIKSEGISGIYKGLTPTILKQGSNQAIRFFVLESLKDLYKGDDHTKPVPKLVVG 232
                    ...:::|.||:|:||||..|:|:......:.|.:..:|..|.:.....|. |..|..
Human   191 PRPTATQLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKS-PFYVSF 254

  Fly   233 VFGAIAGAASVFGNTPLDVVKTRMQ----GLEASKYKNTAHCAVEILKNEGPAAFYKGTVPR 290
            :.|.:||:|:.....|.||||||:|    |:....|.....||.:||::|||:||.||...|
Human   255 LAGCVAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCR 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sea	NP_001027175.1	Mito_carr	34..117	CDD:395101	29/108 (27%)
		Mito_carr	125..220	CDD:395101	36/126 (29%)
		Mito_carr	235..314	CDD:395101	26/60 (43%)
SLC25A22	NP_001412263.1	PTZ00169	3..314	CDD:240302	95/318 (30%)
		Mito_carr	4..123	CDD:395101	34/125 (27%)