Protein Alignment sea and SLC25A1

DIOPT Version :10

• Sequence 1: NP_001027175.1
• Gene: sea / 3772221
• FlyBaseID: FBgn0037912
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001243463.1
• Gene: SLC25A1 / 6576
• HGNCID: 10979
• Length: 318
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 196/305 - (64%)
• Similarity: 237/305 - (77%)
• Gaps: 10/305 - (3%)

  Fly    12 PYRRRPWMTEHGAAAADSGQVGLKGIVAGGITGGIEICITYPTEYVKTQLQLDEKGAAKKYNGIF 76
            |.|:||      ..:..||    ..:.|||:.||||||||:|||||||||||||:....:|.||.
Human    21 PERQRP------GGSLRSG----FPVPAGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIG 75

  Fly    77 DCVKKTVGERGFLGLYRGLSVLVYGSIPKSAARFGAFEFLKSNAVDSRGQLSNSGKLLCGLGAGV 141
            |||::||...|.||||||||.|:||||||:|.|||.||||.::..|::|:|.::..|||||||||
Human    76 DCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSTRGLLCGLGAGV 140

  Fly   142 CEAIVAVTPMETIKVKFINDQRSGNPKFRGFAHGVGQIIKSEGISGIYKGLTPTILKQGSNQAIR 206
            .||:|.|.||||||||||:||.|.|||:|||.|||.:|::.:|:.|.|:|||.|:||||||||||
Human   141 AEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIR 205

  Fly   207 FFVLESLKDLYKGDDHTKPVPKLVVGVFGAIAGAASVFGNTPLDVVKTRMQGLEASKYKNTAHCA 271
            |||:.||::.|:||:..||:..|:.||||||||||||||||||||:|||||||||.||:||..|.
Human   206 FFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLEAHKYRNTWDCG 270

  Fly   272 VEILKNEGPAAFYKGTVPRLGRVCLDVAITFMIYDSFMDLFNKVW 316
            ::|||.||..|||||||||||||||||||.|:|||..:.|.||||
Human   271 LQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLLNKVW 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sea	NP_001027175.1	Mito_carr	34..117	CDD:395101	55/82 (67%)
		Mito_carr	125..220	CDD:395101	61/94 (65%)
		Mito_carr	235..314	CDD:395101	60/78 (77%)
SLC25A1	NP_001243463.1	Mito_carr	38..121	CDD:395101	56/82 (68%)
		Mito_carr	<148..220	CDD:395101	47/71 (66%)
		Mito_carr	223..313	CDD:395101	66/89 (74%)