DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sea and aralar1

DIOPT Version :9

Sequence 1:	NP_001027175.1	Gene:	sea / 3772221	FlyBaseID:	FBgn0037912	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_001247368.1	Gene:	aralar1 / 43616	FlyBaseID:	FBgn0028646	Length:	707	Species:	Drosophila melanogaster

Alignment Length:	320	Identity:	90/320 - (28%)
Similarity:	140/320 - (43%)	Gaps:	40/320 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DRSAFAS-LVSPYRRRPWMTEHGAAAADSGQVGLKGIVAGGITGGIEICITYPTEYVKTQLQLDE 65
            |||||.. |.|.||                      ...|...|.:...:.||.:.|||::|...
  Fly   344 DRSAFIQVLESSYR----------------------FTLGSFAGAVGATVVYPIDLVKTRMQNQR 386

  Fly    66 KGA---AKKYNGIFDCVKKTVGERGFLGLYRGLSVLVYGSIPKSAARFGAFEFLKSNAVDSRGQL 127
            .|:   ...|...:||.||.|...||:||||||...:.|..|:.|.:....:.::....|.:|.:
  Fly   387 AGSYIGEVAYRNSWDCFKKVVRHEGFMGLYRGLLPQLMGVAPEKAIKLTVNDLVRDKLTDKKGNI 451

  Fly   128 SNSGKLLCGLGAGVCEAIVAVTPMETIKVKF-INDQRSGNPKFRGFAHGVGQIIKSEGISGIYKG 191
            ....::|.|..||..: :|...|:|.:|::. :..:.:...|.|.::     :::..|:.|:|||
  Fly   452 PTWAEVLAGGCAGASQ-VVFTNPLEIVKIRLQVAGEIASGSKIRAWS-----VVRELGLFGLYKG 510

  Fly   192 LTPTILKQGSNQAIRFFVLESLKDLYKG-DDHTKPVPKLVVGVFGAIAGAASVFGNTPLDVVKTR 255
            ....:|:.....||.|......|.:... |.:..|:..|..   |||||..:....||.||:|||
  Fly   511 ARACLLRDVPFSAIYFPTYAHTKAMMADKDGYNHPLTLLAA---GAIAGVPAASLVTPADVIKTR 572

  Fly   256 MQGLEAS---KYKNTAHCAVEILKNEGPAAFYKGTVPRLGRVCLDVAITFMIYDSFMDLF 312
            :|.:..|   .|........:|:..|||.||:|||..|:.|......:|.:.|:....||
  Fly   573 LQVVARSGQTTYTGVWDATKKIMAEEGPRAFWKGTAARVFRSSPQFGVTLVTYELLQRLF 632

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sea	NP_001027175.1	PTZ00168	34..302	CDD:185494	77/275 (28%)
		Mito_carr	34..117	CDD:278578	26/85 (31%)
		Mito_carr	125..220	CDD:278578	21/96 (22%)
		Mito_carr	235..314	CDD:278578	30/81 (37%)
aralar1	NP_001247368.1	EF-hand_7	35..99	CDD:290234
		EF-hand_8	51..99	CDD:290545
		EF-hand_7	81..134	CDD:290234
		EFh	84..135	CDD:298682
		EF-hand_7	111..173	CDD:290234
		Mito_carr	350..448	CDD:278578	31/119 (26%)
		PTZ00169	358..631	CDD:240302	79/281 (28%)
		Mito_carr	449..539	CDD:278578	21/95 (22%)
		Mito_carr	544..633	CDD:278578	32/92 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441999
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840