Protein Alignment sea and SLC25A47

DIOPT Version :10

• Sequence 1: NP_001027175.1
• Gene: sea / 3772221
• FlyBaseID: FBgn0037912
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_997000.2
• Gene: SLC25A47 / 283600
• HGNCID: 20115
• Length: 308
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 87/314 - (27%)
• Similarity: 138/314 - (43%)
• Gaps: 55/314 - (17%)

  Fly    38 VAGGITGGIEICITYPTEYVKTQLQLDEKGAAKKYNGIFDCVKKTVGERGFLGLYRGLSVLVYGS 102
            |||.|.|...:.:.||.:.||.::|.:     .||.||:.||:.|.......|.|||||:.|...
Human     4 VAGAIGGVCGVAVGYPLDTVKVRIQTE-----PKYTGIWHCVRDTYHRERVWGFYRGLSLPVCTV 63

  Fly   103 IPKSAARFGAF----------EFLKSNAVDSRGQLSNSGKLLCGLGAGVCEAIVAVTPMETIKVK 157
            ...|:..||.:          .:...:|..::..::.||   |..|   ...:...:|.|..||:
Human    64 SLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSG---CASG---LVRVFLTSPTEVAKVR 122

  Fly   158 F------INDQR----SG---------------NPKFRGFAHGVGQIIKSEGISGIYKGLTPTIL 197
            .      ...||    ||               .||:||..|.:..:.:.||:.|:|||.:..:|
Human   123 LQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYKGSSALVL 187

  Fly   198 KQGSNQAIRFFVLESLKDLYKGDDHTKP-VPKLVV--GVFGAIAGAASVFGNTPLDVVKTRMQ-- 257
            :.|.:.|..|.....|.:......|::| ||.::|  |..|.:|.|.:    ||:||:|:|:|
Human   188 RDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVA----TPMDVIKSRLQAD 248

  Fly   258 GLEASKYKNTAHCAVEILKNEGPAAFYKGTVPRLGRVCLDVAITFMIYDSFMDL 311
            |....:|:...||.|..::.|||...:||.|....|......:.|:.|::.:.|
Human   249 GQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYEAVLRL 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sea	NP_001027175.1	Mito_carr	34..117	CDD:395101	27/88 (31%)
		Mito_carr	125..220	CDD:395101	28/119 (24%)
		Mito_carr	235..314	CDD:395101	25/79 (32%)
SLC25A47	NP_997000.2	Solcar 1	1..80		27/80 (34%)
		Mito_carr	2..77	CDD:395101	27/77 (35%)
		Solcar 2	93..206		28/118 (24%)
		Mito_carr	100..208	CDD:395101	28/113 (25%)
		Solcar 3	215..302		29/90 (32%)
		Mito_carr	221..302	CDD:395101	26/84 (31%)