Protein Alignment sea and SLC25A30

DIOPT Version :10

• Sequence 1: NP_001027175.1
• Gene: sea / 3772221
• FlyBaseID: FBgn0037912
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: XP_005266378.1
• Gene: SLC25A30 / 253512
• HGNCID: 27371
• Length: 293
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 70/294 - (23%)
• Similarity: 120/294 - (40%)
• Gaps: 62/294 - (21%)

  Fly    35 KGIVAGGITGGIEICITYPTEYVKTQLQL-----DEKGAAKKYNGIFDCVKKTVGERGFLGLYRG 94
            |..|.||:......|.|:|.:..||:||:     |.|....:|.|:...:.:...|.|...||.|
Human     7 KPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALYSG 71

  Fly    95 LSVLV-----YGSIPKSAARFGAFEFLKSNAVDSRGQLSNSGKLLCGLGAGVCEAIVAVTPMETI 154
            ::..:     ||:|     :.|.::.||...::.....:....::||:.:||..:.:| .|.:.:
Human    72 IAPAMLRQASYGTI-----KIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIA-NPTDVL 130

  Fly   155 KVKFINDQRSGNPKFRGFAHGVGQIIKSEGISGIYKGLTPTILKQGSNQAIRFFVLESLKDLYK- 218
            |::.   |...|....|.......|.:.||..|::||::.|    ....||...|...:.|:.|
Human   131 KIRM---QAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLT----AQRAAIVVGVELPVYDITKK 188

  Fly   219 --------GDD-HTKPVPKLVVGVFGAIAGAASVFGNTPLDVVKTRMQGLEASKYKNTAHCAVEI 274
                    ||. :|..:.....|:.||:|       :.|:|||:|||..              :.
Human   189 HLILSGLMGDTVYTHFLSSFTCGLAGALA-------SNPVDVVRTRMMN--------------QR 232

  Fly   275 LKNEGPAAFYKGTVPRLGRVCLDVAITFMIYDSF 308
            :..:|..:.|.||        ||..:...:.:||
Human   233 VLRDGRCSGYTGT--------LDCLLQLTVLESF 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sea	NP_001027175.1	Mito_carr	34..117	CDD:395101	24/91 (26%)
		Mito_carr	125..220	CDD:395101	22/103 (21%)
		Mito_carr	235..314	CDD:395101	18/74 (24%)
SLC25A30	XP_005266378.1	Mito_carr	5..100	CDD:395101	26/97 (27%)
		Mito_carr	102..191	CDD:395101	22/96 (23%)
		Mito_carr	199..>252	CDD:395101	18/81 (22%)