DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sea and K11H3.3

DIOPT Version :9

Sequence 1:	NP_001027175.1	Gene:	sea / 3772221	FlyBaseID:	FBgn0037912	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_499187.1	Gene:	K11H3.3 / 176398	WormBaseID:	WBGene00010780	Length:	312	Species:	Caenorhabditis elegans

Alignment Length:	283	Identity:	196/283 - (69%)
Similarity:	233/283 - (82%)	Gaps:	0/283 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 LKGIVAGGITGGIEICITYPTEYVKTQLQLDEKGAAKKYNGIFDCVKKTVGERGFLGLYRGLSVL 98
            ::|||.||||||||||||:|||||||||||||:.|..|:.|..||||:||...||.|||||||||
Worm    26 VRGIVIGGITGGIEICITFPTEYVKTQLQLDERSATPKFRGPIDCVKQTVNGHGFFGLYRGLSVL 90

  Fly    99 VYGSIPKSAARFGAFEFLKSNAVDSRGQLSNSGKLLCGLGAGVCEAIVAVTPMETIKVKFINDQR 163
            :|||||||:.|||.||:|||.|.|.||.||...:||||||||:.||:.|||||||:|||||:||.
Worm    91 LYGSIPKSSFRFGTFEYLKSQAADERGNLSPVMRLLCGLGAGLSEAVFAVTPMETVKVKFIHDQG 155

  Fly   164 SGNPKFRGFAHGVGQIIKSEGISGIYKGLTPTILKQGSNQAIRFFVLESLKDLYKGDDHTKPVPK 228
            ...||::||.||||.|:|:||:.|||||:|.|:.||||||||||||:|:|||.|:|.|:|:|:.|
Worm   156 LAQPKYKGFVHGVGCIVKAEGLGGIYKGVTATMAKQGSNQAIRFFVMETLKDWYRGGDNTQPISK 220

  Fly   229 LVVGVFGAIAGAASVFGNTPLDVVKTRMQGLEASKYKNTAHCAVEILKNEGPAAFYKGTVPRLGR 293
            .:||:.||:||||||:||||:||||||||||||.|||||..||::|.|.||..||||||||||.|
Worm   221 PIVGLMGAVAGAASVYGNTPIDVVKTRMQGLEAKKYKNTLDCAMQIWKKEGFFAFYKGTVPRLSR 285

  Fly   294 VCLDVAITFMIYDSFMDLFNKVW 316
            |||||.||||||||.::..:..|
Worm   286 VCLDVGITFMIYDSIIEFLDVYW 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sea	NP_001027175.1	PTZ00168	34..302	CDD:185494	188/267 (70%)
		Mito_carr	34..117	CDD:278578	60/82 (73%)
		Mito_carr	125..220	CDD:278578	63/94 (67%)
		Mito_carr	235..314	CDD:278578	59/78 (76%)
K11H3.3	NP_499187.1	Mito_carr	<43..109	CDD:278578	46/65 (71%)
		Mito_carr	117..211	CDD:278578	63/93 (68%)
		Mito_carr	225..304	CDD:278578	59/78 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159783
Domainoid	1	1.000	133	1.000	Domainoid score	I3138
eggNOG	1	0.900	-	-		E1_KOG0756
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4362
Inparanoid	1	1.050	408	1.000	Inparanoid score	I1065
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58666
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002928
OrthoInspector	1	1.000	-	-		oto18796
orthoMCL	1	0.900	-	-		OOG6_104005
Panther	1	1.100	-	-	LDO	PTHR45788
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1828
SonicParanoid	1	1.000	-	-		X3276
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790