DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10096 and CER4

DIOPT Version :9

Sequence 1:	NP_001027183.1	Gene:	CG10096 / 3772183	FlyBaseID:	FBgn0038032	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_567936.5	Gene:	CER4 / 829521	AraportID:	AT4G33790	Length:	493	Species:	Arabidopsis thaliana

Alignment Length:	519	Identity:	133/519 - (25%)
Similarity:	232/519 - (44%)	Gaps:	116/519 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MATDVQ-----SFYKDKTVFLTGGSGFLGKVTIAKLL-CTTEVKRIYVLLRAKRGQEMRERCAAW 59
            |:|:::     .:..:|::.:.|.:|||..:.:.|:| ....||::|:||||.:|:...:|   :
plant     1 MSTEMEVVSVLKYLDNKSILVVGAAGFLANIFVEKILRVAPNVKKLYLLLRASKGKSATQR---F 62

  Fly    60 DKDPVFGNLMKT---------NPEALKRVVPCGGDCQEPDLGLSNSD-RQVLIDEVQIVIHTAAT 114
            :.:.:..:|.|.         |....:::....||....||||.:.| ...:|.:|..:::.|||
plant    63 NDEILKKDLFKVLKEKYGPNLNQLTSEKITIVDGDICLEDLGLQDFDLAHEMIHQVDAIVNLAAT 127

  Fly   115 VRFVEPLHIALAVNTRATRLMIQLAKEMSHLESFVHVSTAY-----SNCVVE---HVSERF---- 167
            .:|.|...:||.:||.....::..||..:.::..|||||||     |..::|   .:.|..
plant   128 TKFDERYDVALGINTLGALNVLNFAKRCAKVKILVHVSTAYVCGEKSGLIMETPYRMGETLNGTT 192

  Fly   168 -----YPEHLTCPAEKILELL------ESISPELLD-KMAPALMGKYPNTYTYTKALTEQVIQKE 220
                 |.:.|.  .||:.:|.      |:|:..:.| .:..|.|..:||||.:|||:.|.::..:
plant   193 GLDINYEKKLV--QEKLDQLRVIGAAPETITETMKDLGLRRAKMYGWPNTYVFTKAMGEMMVGTK 255

  Fly   221 AKDLPLSIFRPGVIIASYKEPMPGWIDNL--YGPIAVLYGAAFGILHITLLNLKAQAGIVPVDYC 283
            .::|.|.:.||.:|.:::|||.|||.:.:  ...:||.||.  |.|...|.:|.|.:.::|.|..
plant   256 RENLSLVLLRPSIITSTFKEPFPGWTEGIRTIDSLAVGYGK--GKLTCFLCDLDAVSDVMPADMV 318

  Fly   284 VNMVL-TCAWNTARDTSIKLSPEPPIYNFTPNNDNLITWGGFRDKAARLRYTYPLTKMMWLPFLH 347
            ||.:| :.|....:...|       ||:.                .:.||.....:|...|.:.:
plant   319 VNSILVSMAAQAGKQEEI-------IYHV----------------GSSLRNPMKNSKFPELAYRY 360

  Fly   348 CTTIPW---------------------LFRFTAIFYHLLPGYAIDLALRLWGKKPRMIKLYDK-- 389
            .:..||                     ..|:..|.| |:....::|...:      :.||::|
plant   361 FSIKPWTNKEGKVVKVGAIEILSSMRSFHRYMTIRY-LIALKGLELVNII------LCKLFEKEF 418

  Fly   390 ---------IHKNIDILAPFVITSWSFDTVNT---RKLWAKMSVEDQKLYDFNMSSVDWDDYFL 441
                     |.:.:|:..|::.....||..||   ||:.:|..||::..| |:...:|||||||
plant   419 QYFNKKINFIFRLVDLYQPYLFFYGIFDDSNTEKLRKMVSKTGVENEMFY-FDPKVLDWDDYFL 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10096	NP_001027183.1	PLN02996	1..441	CDD:215538	131/517 (25%)
		FAR-N_SDR_e	12..330	CDD:187547	96/355 (27%)
		Sterile	363..453	CDD:281068	26/93 (28%)
CER4	NP_567936.5	PLN02996	6..493	CDD:215538	131/514 (25%)
		FAR-N_SDR_e	17..365	CDD:187547	100/377 (27%)
		Sterile	396..493	CDD:281068	27/94 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.960