DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10096 and CG34342

DIOPT Version :9

Sequence 1:	NP_001027183.1	Gene:	CG10096 / 3772183	FlyBaseID:	FBgn0038032	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_001097509.3	Gene:	CG34342 / 5740152	FlyBaseID:	FBgn0085371	Length:	572	Species:	Drosophila melanogaster

Alignment Length:	502	Identity:	174/502 - (34%)
Similarity:	279/502 - (55%)	Gaps:	27/502 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ATDVQSFYKDKTVFLTGGSGFLGKVTIAKLLCTTEVKRIYVLLRAKRGQEMRERCAAWDKDPVFG 66
            ||.|..||.:.||.:|||:||:|||...|||.:..:::||:|:|:|....::||...:..:.:|.
  Fly    67 ATPVTDFYSNATVLITGGTGFVGKVLTEKLLRSFGLRKIYMLIRSKDNMSVQERLKGFFNESIFN 131

  Fly    67 NLMKTNPEALKRVVPCGGDCQEPDLGLSNSDRQVLIDEVQIVIHTAATVRFVEPLHIALAVNTRA 131
            .:.:.:|:.|.:|.|...|....||.:.::||.:|..|||||.:..|:|:|.|.|..|:.:|...
  Fly   132 RMREESPQLLAKVHPIRADYSAIDLDIDSADRAMLSSEVQIVFNVVASVKFNEKLSDAIDINVLG 196

  Fly   132 TRLMIQLAKEMSHLESFVHVSTAYSNCVVEHVSERFYPEHLTCPAEKILELLESISPELLDKMAP 196
            |:.::.|..||.||:||||:||.|.||..:.:.|:.|...:  ..|||:::..:...|.|:||..
  Fly   197 TKKILDLVMEMKHLKSFVHISTLYCNCNRKFIKEQVYENEI--GYEKIMQIYRTFDDETLEKMRH 259

  Fly   197 ALMGKYPNTYTYTKALTEQVIQKEAKDLPLSIFRPGVIIASYKEPMPGWIDNLYGPIAVLYGAAF 261
            .|:|:.|||||.||...|.::...|..:|..||||.:::::||:|.|||.||||||..:...:|.
  Fly   260 CLIGQMPNTYTMTKKCAENLVNHRAFHMPAGIFRPPIVMSTYKDPFPGWTDNLYGPSGLCTWSAR 324

  Fly   262 GILHITLLNLKAQAGIVPVDYCVNMVLTCAWNTA-----RDTSIKLSPEPPIYNFTPNNDNLITW 321
            |::.........:|.:||.||.||.::..||:.|     |::.:....|.|:||:..:.:| |||
  Fly   325 GLVRCIYGKASCKANMVPADYVVNAMIATAWDIARRFKLRESKVDGKSELPVYNYVSDANN-ITW 388

  Fly   322 GGFRDKAARLRYTYPLTKMMW------LPF--LHCTTIPWLFRFTAIFYHLLPGYAIDLALRLWG 378
            |.:. ..:|..:..|..|.:|      :|.  |||.        .|.|.|.:|.|.:||...:.|
  Fly   389 GQYM-HLSRKGFHEPFDKALWCFSYVIIPSKPLHCA--------IAFFLHNIPAYILDLIAMVTG 444

  Fly   379 KKPRMIKLYDKIHKNIDILAPFVITSWSFDTVNTRKLWAKMSVEDQKLYDFNMSSVDWDDYFLQA 443
            :|....|.|.||.:.||::|.|.:..|.|...|..:|...:..|::.:..||:::::|.:||...
  Fly   445 QKRIYAKAYGKISRIIDMMAWFGLKEWKFAHRNIDELNELLPREERSVLQFNIATINWSEYFRSY 509

  Fly   444 LAGVRIYLAKEEPGQEVVERGRKIYKRFEFLHRLLQFTLCGGAALIL 490
            |:|:|.|..|:......:::.|.||:|...||.||:.|.  |.:||:
  Fly   510 LSGIRRYFFKDSANDNKLQQRRTIYRRMLILHTLLKTTF--GLSLIM 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10096	NP_001027183.1	PLN02996	1..441	CDD:215538	156/451 (35%)
		FAR-N_SDR_e	12..330	CDD:187547	117/322 (36%)
		Sterile	363..453	CDD:281068	29/89 (33%)
CG34342	NP_001097509.3	PLN02996	70..519	CDD:215538	159/460 (35%)
		FAR-N_SDR_e	78..397	CDD:187547	117/322 (36%)
		Sterile	429..519	CDD:281068	29/89 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466718
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	8	7.990