DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10096 and CG4770

DIOPT Version :9

Sequence 1:	NP_001027183.1	Gene:	CG10096 / 3772183	FlyBaseID:	FBgn0038032	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_650848.1	Gene:	CG4770 / 42375	FlyBaseID:	FBgn0038751	Length:	490	Species:	Drosophila melanogaster

Alignment Length:	497	Identity:	154/497 - (30%)
Similarity:	257/497 - (51%)	Gaps:	41/497 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TDVQSFYKDKTVFLTGGSGFLGKVTIAKLLCT-TEVKRIYVLLRAKRGQEMRERCAAWDKDPVFG 66
            ||:   |:|..||:||.:||:||..:.|||.: .::||||:|:|.|.|..:.||...:.::|:|.
  Fly    13 TDI---YQDAVVFITGATGFVGKSLLEKLLWSFPQIKRIYMLIRPKGGVTVEERFRGFLQNPIFE 74

  Fly    67 NLMKTNPEALKRVVPCGGDCQEPDLGLSNSDRQVLIDEVQIVIHTAATVRFVEPLHIALAVNTRA 131
            .:...:|..||::....|:.::.:|||:.|||.||..||.|:.|:||||||.|.|.::..||::|
  Fly    75 RIKSEHPTQLKKIFHFSGNIEDDNLGLNESDRSVLCAEVNIIFHSAATVRFNECLKVSARVNSQA 139

  Fly   132 TRLMIQLAKEMSHLESFVHVSTAYSNCVVEHVSERFYPEHLTCPAEKILELLESISPELLDKMAP 196
            |..:::|.::|.:|.||::|||||.|...::|.|:.||........:.|...:.|..:.|:::|.
  Fly   140 TYNLLELCRQMPYLRSFLYVSTAYCNPGRKYVDEQVYPTMPPVDWRQFLSATQKIPDDYLNRLAD 204

  Fly   197 ALMGKYPNTYTYTKALTEQVIQKEAKDLPLSIFRPGVIIASYKEPMPGWIDNLYGPIAVLYGAAF 261
            .:.|.:.||||:||::.||::......:|:.|.||.::.|:|:||.||||||:.....::.....
  Fly   205 YIKGPHVNTYTFTKSIAEQIVNAYKDVIPIVIVRPSIVTAAYREPYPGWIDNIQAISGIMMEIGK 269

  Fly   262 GILHITLLNLKAQAGIVPVDYCVNMVLTCAWNTARDTSIKLSPEPPIYNFTPNNDNLITWGGFRD 326
            |.:...|.|......|:|||:.||.::... ..|:..|:.      |.|.|....|.|||....:
  Fly   270 GGISSILGNKDLICDIIPVDFVVNAMIMMV-GKAKLGSLS------ICNATSGVTNPITWQHLGE 327

  Fly   327 KAARLRYTYPLTKMMWLP--------FLHCTTIPWLFRFTAIFYHLLPGYAIDLALRLWGKKPRM 383
            ...:....||..:|:..|        |.|...: |:.       |.:|...:||...|..:|.|:
  Fly   328 LTMKWSRIYPTRRMIMFPNFKYRCSAFNHELAV-WVL-------HFVPALLMDLQTLLLAQKKRL 384

  Fly   384 IKLYDKIHKNIDILAPFV-ITSWSFDTVNTRKLWAKMSVED---QKLYDFNMSSVDWDDYFLQAL 444
            :....|..:...:...|. :..|.|.  |..:.:.|..:|:   ..|| :|:..:|:|:|..:.:
  Fly   385 VTPIAKKFRQACLAGSFFSLNEWIFK--NKSRFYFKEMIENGTYPTLY-WNLEEMDYDEYVRRHM 446

  Fly   445 AGVRIYLAKE----EPGQEVVERGRKIYKRFEFLHRLLQFTL 482
            .|:..||.:|    :..:.:|.|   ||..:.|||.:....|
  Fly   447 IGINKYLHREKFTVDSNKFMVTR---IYWFWIFLHLMFYMML 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10096	NP_001027183.1	PLN02996	1..441	CDD:215538	142/450 (32%)
		FAR-N_SDR_e	12..330	CDD:187547	111/318 (35%)
		Sterile	363..453	CDD:281068	23/93 (25%)
CG4770	NP_650848.1	WcaG	21..358	CDD:223528	117/343 (34%)
		FAR-N_SDR_e	21..337	CDD:187547	111/322 (34%)
		Sterile	364..455	CDD:281068	23/93 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466725
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	9	8.890