DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10096 and CG17562

DIOPT Version :9

Sequence 1:	NP_001027183.1	Gene:	CG10096 / 3772183	FlyBaseID:	FBgn0038032	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_650566.1	Gene:	CG17562 / 42021	FlyBaseID:	FBgn0038449	Length:	499	Species:	Drosophila melanogaster

Alignment Length:	499	Identity:	282/499 - (56%)
Similarity:	358/499 - (71%)	Gaps:	1/499 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MATDVQSFYKDKTVFLTGGSGFLGKVTIAKLLCTTEVKRIYVLLRAKRGQEMRERCAAWDKDPVF 65
            |.||:|..::.|||||||.:||||||.|.|||.||||||||||:|.|||.|:::|...|.||.||
  Fly     1 MDTDIQRCFRSKTVFLTGATGFLGKVVIEKLLRTTEVKRIYVLIRPKRGVEIKDRIITWSKDAVF 65

  Fly    66 GNLMKTNPEALKRVVPCGGDCQEPDLGLSNSDRQVLIDEVQIVIHTAATVRFVEPLHIALAVNTR 130
            ..|:|:.||||:||.|..|||.:.|||:|.:||::|..|||||||.||||||.||||:|||:|||
  Fly    66 ELLLKSKPEALQRVCPIAGDCLDFDLGISENDRRLLASEVQIVIHGAATVRFNEPLHVALAINTR 130

  Fly   131 ATRLMIQLAKEMSHLESFVHVSTAYSNCVVEHVSERFYPEHLTCPAEKILELLESISPELLDKMA 195
            ||:|||||||||..||:|||||||:||||:.::.|.||||||.|.::|:|.:.|.:|.||||.|.
  Fly   131 ATKLMIQLAKEMRQLEAFVHVSTAFSNCVIYNIKENFYPEHLNCSSDKVLAMAELMSDELLDNME 195

  Fly   196 PALMGKYPNTYTYTKALTEQVIQKEAKDLPLSIFRPGVIIASYKEPMPGWIDNLYGPIAVLYGAA 260
            .||:|.:||||||||||.|.||.|||..|||.||||.||||::|||:.|||||:|||:|:|:|.|
  Fly   196 QALLGSFPNTYTYTKALAEDVILKEAGGLPLCIFRPAVIIAAHKEPISGWIDNMYGPMAILFGVA 260

  Fly   261 FGILHITLLNLKAQAGIVPVDYCVNMVLTCAWNTARDTSIKLSPEPP-IYNFTPNNDNLITWGGF 324
            .|:|.|..::..|:|.:||||||.|:.|.|.|.|..:.:...:.|.| ||...|...|.||.|.|
  Fly   261 RGVLRIATIDHHAEASLVPVDYCANLTLACTWKTIVEGNEMGTQETPLIYQLAPIEQNKITHGEF 325

  Fly   325 RDKAARLRYTYPLTKMMWLPFLHCTTIPWLFRFTAIFYHLLPGYAIDLALRLWGKKPRMIKLYDK 389
            ...|...|...|||||:|.||:||.|:||||...|.|||.||.|..||||.|.|:|||::|:|.|
  Fly   326 IRHALDGRTNCPLTKMIWYPFIHCITVPWLFPLAAFFYHTLPAYFFDLALWLSGRKPRLVKVYQK 390

  Fly   390 IHKNIDILAPFVITSWSFDTVNTRKLWAKMSVEDQKLYDFNMSSVDWDDYFLQALAGVRIYLAKE 454
            |||.:.||.||...||.||..||..|..:||.||:::|.|:|.|::|.:||:|||.|:|.:|..|
  Fly   391 IHKTLGILGPFACKSWRFDMRNTDHLRQQMSEEDRRIYYFDMVSLNWKEYFVQALRGMRQFLGNE 455

  Fly   455 EPGQEVVERGRKIYKRFEFLHRLLQFTLCGGAALILWSILKRLL 498
            .|..|.:.:|:|:.||.:.||.:||..||..|.|.|||:::.|:
  Fly   456 APTPESIAQGKKLIKRLKLLHHILQGVLCFVALLALWSLVRILV 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10096	NP_001027183.1	PLN02996	1..441	CDD:215538	256/440 (58%)
		FAR-N_SDR_e	12..330	CDD:187547	193/318 (61%)
		Sterile	363..453	CDD:281068	47/89 (53%)
CG17562	NP_650566.1	PLN02996	10..442	CDD:215538	252/431 (58%)
		FAR-N_SDR_e	12..329	CDD:187547	192/316 (61%)
		FAR_C	362..452	CDD:176924	48/89 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466699
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	9	8.890