DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10096 and far1

DIOPT Version :9

Sequence 1:	NP_001027183.1	Gene:	CG10096 / 3772183	FlyBaseID:	FBgn0038032	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	XP_005174372.1	Gene:	far1 / 406829	ZFINID:	ZDB-GENE-040426-2908	Length:	518	Species:	Danio rerio

Alignment Length:	497	Identity:	174/497 - (35%)
Similarity:	262/497 - (52%)	Gaps:	24/497 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VQSFYKDKTVFLTGGSGFLGKVTIAKLLCTTE-VKRIYVLLRAKRGQEMRERCAAWDKDPVFGNL 68
            :..:|..|.|.:||.:||:|||.:.|||.:.. ||..|||:|.|.||....|.|......:|..|
Zfish     4 IPEYYVGKNVLITGATGFMGKVLLEKLLRSCPGVKAAYVLVRPKAGQAPDARIADMINCKLFDRL 68

  Fly    69 MKTNPEALKRVVPCGGDCQEPDLGLSNSDRQVLIDEVQIVIHTAATVRFVEPLHIALAVNTRATR 133
            .:..|:...::|....|..:|:|.||..|::.|...:.:|.|.|||:||.|||..|:.:|..||:
Zfish    69 REDQPDFAGKIVAINSDLTQPNLDLSAEDQETLTGCINVVFHCAATIRFNEPLKDAMQLNVLATQ 133

  Fly   134 LMIQLAKEMSHLESFVHVSTAYSNCVVEHVSERFYPEHLTCPAE--KILELLESISPELLDKMAP 196
            .|:.||..|.|||.|:||||||:||..|.:.|..||.    |.:  |:::.||.:..:|:..|.|
Zfish   134 KMVSLAHRMKHLEVFIHVSTAYANCDRELIEEVVYPP----PVDYRKLIDTLEWMDDKLVSLMTP 194

  Fly   197 ALMGKYPNTYTYTKALTEQVIQKEAKDLPLSIFRPGVIIASYKEPMPGWIDNLYGPIAVLYGAAF 261
            .|:|:.||||||||||.||::|:|..:|.::|.||.::.||:|||.||||||..||..:...|..
Zfish   195 RLLGERPNTYTYTKALAEQLVQQECGNLNIAIIRPSIVGASWKEPFPGWIDNFNGPSGIFIAAGK 259

  Fly   262 GILHITLLNLKAQAGIVPVDYCVNMVLTCAWNT-----ARDTSIKLSPEPPIYNFTPNNDNLITW 321
            |||.....:..|.|.:||||..:|..|..||.:     ||..|:.      :||.|....|...|
Zfish   260 GILRTMRASNNAVADLVPVDVVINTTLAAAWYSGSQRHARPRSLL------VYNCTTGGINPFHW 318

  Fly   322 GGFRDKAARLRYTYPLTKMMWLPFLHCTTIPWLFRFTAIFYHLLPGYAIDLALRLWGKKPRMIKL 386
            |.............||.:....|.::.||...:.::.....|..|.:..||.||:.|::|||:|.
Zfish   319 GEVEYHVISTFKRNPLEQAFRRPNVNLTTNHLINQYWIAVSHKAPAFLYDLFLRMSGREPRMMKT 383

  Fly   387 YDKIHKNIDILAPFVITSWSFDTVNTRKLWAKMSVEDQKLYDFNMSSVDWDDYFLQALAGVRIYL 451
            ..::||.:.:|..|...||.::|.|...|..:|..||:|:::|::..:.|.:|......|.:.|:
Zfish   384 ITRLHKAMMVLEYFTSHSWVWNTDNVTMLMNQMGAEDKKVFNFDVRQLHWAEYMENYCMGTKKYV 448

  Fly   452 AKEEPGQEVVERGRKIYKRFEFLHRLLQFTLCGGAALILWSI 493
            ..||  ...:...||...:.    |.:::|......:::|.|
Zfish   449 LNEE--LSGLPAARKHLNKL----RNIRYTFNTVLVVLIWRI 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10096	NP_001027183.1	PLN02996	1..441	CDD:215538	164/443 (37%)
		FAR-N_SDR_e	12..330	CDD:187547	131/325 (40%)
		Sterile	363..453	CDD:281068	29/89 (33%)
far1	XP_005174372.1	FAR-N_SDR_e	11..333	CDD:187547	131/331 (40%)
far1	XP_005174372.1	Sterile	360..450	CDD:308580	29/89 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593268
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840