DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10096 and CG8303

DIOPT Version :9

Sequence 1:	NP_001027183.1	Gene:	CG10096 / 3772183	FlyBaseID:	FBgn0038032	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_001286495.1	Gene:	CG8303 / 36858	FlyBaseID:	FBgn0034143	Length:	543	Species:	Drosophila melanogaster

Alignment Length:	526	Identity:	153/526 - (29%)
Similarity:	243/526 - (46%)	Gaps:	60/526 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VQSFYKDKTVFLTGGSGFLGKVTIAKLLCT-TEVKRIYVLLRAKRGQEMRERCAAWDKDPVFGNL 68
            :..|:..|.:|:|||:||||.|.|..||.| .::..||||:|.||..:..||.....:.|:|
  Fly    39 IPEFFAHKNIFVTGGTGFLGTVLIEALLDTHPDIGTIYVLVRGKRKFDPNERIRRLLQKPIF--- 100

  Fly    69 MKTNPEALKRVVPCGGDCQEPDLGLSNSDRQVLIDEVQIVIHTAATVRFVEPLHIALAVNTRATR 133
            .|.:.:.|.:|||..|:..||:.|......|.|||.|.::.|:|||::|..||..|:..|...|.
  Fly   101 EKYSEKTLSKVVPVVGELSEPNFGFGPELLQELIDRVNVIYHSAATIKFSSPLRTAIRTNLTGTM 165

  Fly   134 LMIQLAKEMSHLESFVHVSTAYSN-----CVVEHV-SERFYPEHLTCPAEKILELLESISPELLD 192
            ..|:|||::..|.::::.|||:.|     .:.|.| ..:|.|..:...||.     :|...:..|
  Fly   166 RTIELAKQLKQLAAYIYCSTAFCNSNNRGLIAEEVYKSQFDPYEMMKMAED-----DSAWEDFTD 225

  Fly   193 KMAPALMGKYPNTYTYTKALTEQVIQKEAKDLPLSIFRPGVIIASYKEPMPGWIDNL-YGPIAVL 256
            :.....:..:|||||:||.|:|.::..|...||.:|.||.::..:.:.||.||:.|. .|.:..|
  Fly   226 QKCKGYIRDHPNTYTFTKNLSENLLMAEMSGLPAAIVRPSIVYGTLEHPMKGWVGNANSGHLGFL 290

  Fly   257 YGAAFGILHITLLNLKAQAGIVPVDYCVNMVLTCAWNTARDTSIKLSPEPPIYNFTPNNDNLITW 321
            .|...||......|..|...|:|.||.:|..|...|...   :.||. :|.|.:.|....|.:..
  Fly   291 AGFVKGIFRTMCGNANAVIDIIPCDYVINSSLVMGWYVG---TRKLE-QPEIIHCTSGEVNPLNL 351

  Fly   322 GGF----RDKAARLRYTYPLTKMMWLPFLHCTTIPWLFRFTAIFY--HLLPGYAIDLALRLWG-K 379
            ..|    .|...|    :|....:|.|   .|.:...:|:...||  ||||.....:..:|:| .
  Fly   352 AEFCTIINDSVER----HPPNSFVWKP---VTKLRNGWRYNLFFYLFHLLPAMVFIIPEKLFGIG 409

  Fly   380 KPR-----MIKLYDKIHKNIDILAPFVITSWSFDTVNTRKLWAKMSVEDQKLYDFNMSSVDWDDY 439
            .|:     .::::.|..|..|.   |:...:.:...|..::.|.:...|::.|:|:.|..||.::
  Fly   410 MPQHTAYEYMRVFQKGTKAFDY---FLDKDFRYSLKNALRISALIPESDRRRYNFDASQCDWSEF 471

  Fly   440 FLQALAGVRIYLAKEEPGQEVVERGRKIYKRFEFLH--------RLLQF--TLCGG------AAL 488
            ..:.|.|:|.:..||  .....:..|..:|.|..|:        .:|.|  ||..|      .|:
  Fly   472 IDRCLIGIRRFYFKE--SAVTTDWHRNYWKVFNVLYYAGYVVIFAVLYFALTLTLGLQIGLTLAV 534

  Fly   489 ILWSIL 494
            ::|..|
  Fly   535 LIWGFL 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10096	NP_001027183.1	PLN02996	1..441	CDD:215538	136/455 (30%)
		FAR-N_SDR_e	12..330	CDD:187547	108/329 (33%)
		Sterile	363..453	CDD:281068	22/95 (23%)
CG8303	NP_001286495.1	FAR-N_SDR_e	46..366	CDD:187547	109/335 (33%)
CG8303	NP_001286495.1	Sterile	392..485	CDD:281068	22/95 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466792
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.990