DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10096 and CG4020

DIOPT Version :9

Sequence 1:	NP_001027183.1	Gene:	CG10096 / 3772183	FlyBaseID:	FBgn0038032	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_001259264.1	Gene:	CG4020 / 31522	FlyBaseID:	FBgn0029821	Length:	494	Species:	Drosophila melanogaster

Alignment Length:	507	Identity:	168/507 - (33%)
Similarity:	256/507 - (50%)	Gaps:	36/507 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YKDKTVFLTGGSGFLGKVTIAKLL--CTTEVKRIYVLLRAKRGQEMRERCAAWDKDPVFGNLMKT 71
            ::|:.:|:||.|||:||..|.|||  | .::.|||||:|.|:|..:.||.....:..::..|.:.
  Fly     7 FEDQEIFVTGASGFVGKALIEKLLRSC-PKLGRIYVLMRPKKGHTIEERLQLQWESRLYERLRRE 70

  Fly    72 NPEALKRVVPCGGDCQEPDLGLSNSDRQVLIDEVQIVIHTAATVRFVEPLHIALAVNTRATRLMI 136
            .|.|..::|...||.::..||:.::|.:.| ..|.||.|:||:|||.:.|..|:.:|||.|..::
  Fly    71 QPNARSKLVAIAGDVEQLGLGIGSADLERL-RNVNIVYHSAASVRFDDALSTAILLNTRGTHELV 134

  Fly   137 QLAKEMSHLESFVHVSTAYSNCVVEHVSERFYPEHLTCPAEKILELLESISPELLDKMAPALMGK 201
            :||.|...|::||||||.|||..|..|.||.||.  .......::|.|:...|:||.........
  Fly   135 KLALEWPKLKAFVHVSTTYSNPGVLEVEERVYPP--LADWRTTIKLAETYDAEILDIFNLKYGNF 197

  Fly   202 YPNTYTYTKALTEQVIQKEAKDLPLSIFRPGVIIASYKEPMPGWIDNLYGPIAVLYGAAFGILHI 266
            .|||||:||:|.|||:.:....||:.||||.:::::.:||:|||.||..||..:|.....|||..
  Fly   198 QPNTYTFTKSLAEQVVNEYRDRLPIFIFRPSIVVSTIEEPVPGWADNFNGPTGLLVACGVGILRS 262

  Fly   267 TLLNLKAQAGIVPVDYCVNMVLTCAW-------NTARDTSIKLSPEPPIYNFTPNNDNLITWGGF 324
            ...:....|..||.|.....::|..:       :.|:|:.:.      :.|....|.:.||.|..
  Fly   263 QNCDPNIVADFVPADIVARTLITSVYKFMGESKSRAKDSDLY------VVNCATANISPITMGEV 321

  Fly   325 RDKAARLRYTYPLTKMMWLPFLHCTTIPWL--FRFTAIFYHLLPGYAIDLALRLWGKKPRMIKLY 387
            .|.........|..|.:|||....||.|.|  .||..:  |||....:|..|||:.:||.::||.
  Fly   322 IDIGKTFIRKNPFEKTLWLPGGGMTTCPVLHFVRFCTM--HLLMAIVVDTLLRLYNEKPFLMKLQ 384

  Fly   388 DKIHKNIDILAPFVITSWSFDTVNTRKLWAKMSVEDQKLYDF-NMSSVDWDDYFLQALAGVRIYL 451
            .:|......|..|.:|.|.|...|.|.|...:...:...:.| ..:::::.::|...:.|.:.:|
  Fly   385 RRIFAAFSALQVFAMTEWHFQNDNFRALHDVVPANEVSNFGFMQHANINYTEFFQHGIRGAKEFL 449

  Fly   452 AKEEPGQEVVERGR-KIYKRFEFLHRLLQFTLCGGAALILWSILKRLLGSFV 502
            .||.|......|.| ||:...:|        ||.|   |::|.|.||:..|:
  Fly   450 LKESPESSSAARFRVKIFYVLDF--------LCRG---IVYSFLLRLIFRFL 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10096	NP_001027183.1	PLN02996	1..441	CDD:215538	148/443 (33%)
		FAR-N_SDR_e	12..330	CDD:187547	115/326 (35%)
		Sterile	363..453	CDD:281068	24/90 (27%)
CG4020	NP_001259264.1	FAR-N_SDR_e	12..333	CDD:187547	115/330 (35%)
CG4020	NP_001259264.1	FAR_C	359..450	CDD:176924	23/92 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466783
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	9	8.890