DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10096 and far1

DIOPT Version :9

Sequence 1:	NP_001027183.1	Gene:	CG10096 / 3772183	FlyBaseID:	FBgn0038032	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	XP_017948360.1	Gene:	far1 / 100038270	XenbaseID:	XB-GENE-973776	Length:	518	Species:	Xenopus tropicalis

Alignment Length:	458	Identity:	167/458 - (36%)
Similarity:	251/458 - (54%)	Gaps:	16/458 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VQSFYKDKTVFLTGGSGFLGKVTIAKLL--CTTEVKRIYVLLRAKRGQEMRERCAAWDKDPVFGN 67
            :..||:.|.|.:||.:||:|||.:.|||  | ..||.:|||:|.|..|:.|||.|......:|..
Frog     4 IPEFYRGKNVLITGATGFMGKVLLEKLLRSC-PNVKAVYVLVRPKASQKPRERVAEMMSCKLFDR 67

  Fly    68 LMKTNPEALKRVVPCGGDCQEPDLGLSNSDRQVLIDEVQIVIHTAATVRFVEPLHIALAVNTRAT 132
            |....||..::|:....:..:|:|.||..|:.:|||.:.||.|.||||||.|.|..|:.:|..||
Frog    68 LRDEQPECAQKVIAISSELTQPELDLSKEDQDMLIDCIDIVFHCAATVRFNESLRDAMQLNVIAT 132

  Fly   133 RLMIQLAKEMSHLESFVHVSTAYSNCVVEHVSERFYPEHLTCPAEKILELLESISPELLDKMAPA 197
            |.::.||:::..||.|:||||||:||..:.:.|..||..:  ..:|::|.||.:...|::.:.|.
Frog   133 RQLLYLAQKIKKLEVFIHVSTAYANCNRKQIEEMVYPPPV--DPKKLIESLEWMDDGLVNDITPK 195

  Fly   198 LMGKYPNTYTYTKALTEQVIQKEAKDLPLSIFRPGVIIASYKEPMPGWIDNLYGPIAVLYGAAFG 262
            |:|..||||||||||.|.|:|:|...|.::|.||.::.||:|||.||||||..||..:...|..|
Frog   196 LIGDRPNTYTYTKALAEYVVQQEGSKLNIAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKG 260

  Fly   263 ILHITLLNLKAQAGIVPVDYCVNMVLTCAWNT-----ARDTSIKLSPEPPIYNFTPNNDNLITWG 322
            ||.....:..|.|.::|||..||..|..||.:     :|..:|.      :||.|....|...||
Frog   261 ILRTMRASNNAVADLIPVDVVVNTTLAAAWYSGVNRYSRPRNIL------VYNCTTGGTNPFHWG 319

  Fly   323 GFRDKAARLRYTYPLTKMMWLPFLHCTTIPWLFRFTAIFYHLLPGYAIDLALRLWGKKPRMIKLY 387
            .............||.:....|.::.|:...|:.:.....|..|.:..|:.||:.|:.|||:|..
Frog   320 EVEYHVISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAPAFLYDVYLRITGRSPRMMKTI 384

  Fly   388 DKIHKNIDILAPFVITSWSFDTVNTRKLWAKMSVEDQKLYDFNMSSVDWDDYFLQALAGVRIYLA 452
            .::||.:.:|..|...||.::..||..|.:::|.:|:|.::|::..:.|.:|......|.:.|:.
Frog   385 TRLHKAMMLLEYFTSNSWVWNNENTNMLMSQLSPDDKKAFNFDVRQLHWAEYMENYCMGTKKYVL 449

  Fly   453 KEE 455
            .||
Frog   450 NEE 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10096	NP_001027183.1	PLN02996	1..441	CDD:215538	163/442 (37%)
		FAR-N_SDR_e	12..330	CDD:187547	131/324 (40%)
		Sterile	363..453	CDD:281068	27/89 (30%)
far1	XP_017948360.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	83	1.000	Domainoid score	I8217
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910