Protein Alignment Sxl and PABPC4

DIOPT Version :9

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: NP_001129125.1
• Gene: PABPC4 / 8761
• HGNCID: 8557
• Length: 660
• Species: Homo sapiens
• Alignment Length: 480
• Identity: 111/480 - (23%)
• Similarity: 175/480 - (36%)
• Gaps: 134/480 - (27%)

  Fly   117 TNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNGI 181
            ||:.:....:::.|..|..||...|...:.::||| ..|.|.|:.||.:....|:.:|::.:||.
Human   191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGK 254

  Fly   182 TV---------------RNKRLKVSYARPGGESI---KDTNLYVTNLPRTITDDQLDTIFGKYGS 228
            .:               |...||..:.:...|.|   :..|||:.||..||.|::|...|..:||
Human   255 EISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGS 319

  Fly   229 IVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEHGKAKAAHFM 293
            |....::.:  .||.:|..||.::..|||.:|::.:|..|.  ||:||.|.||:...:.| ||..
Human   320 ITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGRIV--GSKPLYVALAQRKEERK-AHLT 379

  Fly   294 SQ-------MGVVPANVPPPPPQPPAHMAAAFNMMHRDGAMEKLRSLFDAICDAIFGLDSENFAD 351
            :|       |..:|||......||.|                                 ...|..
Human   380 NQYMQRVAGMRALPANAILNQFQPAA---------------------------------GGYFVP 411

  Fly   352 LLDGLYRRKYHYPYLXLTPQQQQQLLQH--------QQQALGFTSSSNNS---------IGNGNG 399
            .:.....|..:|     ||.|..|:..:        .|...|..|:...|         ...||.
Human   412 AVPQAQGRPPYY-----TPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGNA 471

  Fly   400 NDNNMLLYHQQYHQQQTQQQRLGNVAAHNISPN----GSNNNINTSNTNNINFNTIRQN-----G 455
            ..:..|         .|..||:|:.....::.:    |:.....|.:..:....|..||     .
Human   472 PASRGL---------PTTTQRVGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAA 527

  Fly   456 VAAL-----------------HYLQEQLQLQQPQDQQSQQQQPLT---MPSSPPFQQQSR----- 495
            |||.                 |...:.||..||. ...|.|:|||   :.::||.:|:..
Human   528 VAAAAPRAVAPYKYASSVRSPHPAIQPLQAPQPA-VHVQGQEPLTASMLAAAPPQEQKQMLGERL 591

  Fly   496 ----QSHHNGSSSTLGNQLLAISNN 516
                |:.|:..:..:...||.|.|:
Human   592 FPLIQTMHSNLAGKITGMLLEIDNS 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	22/94 (23%)
		RRM2_Hu_like	203..281	CDD:240822	29/77 (38%)
PABPC4	NP_001129125.1	PABP-1234	11..640	CDD:130689	111/480 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910