DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sxl and AT2G47310

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_850472.1	Gene:	AT2G47310 / 819344	AraportID:	AT2G47310	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	567	Identity:	118/567 - (20%)
Similarity:	190/567 - (33%)	Gaps:	167/567 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 YGN--NNPGSNNNNGGYPPYGYNNKSSGGRGFGMSHSLP--SGMDTEFSFPSSS----------S 52
            |.|  |||..:..:...||:.:    ....||   |..|  ...|..|:.|..|          |
plant    19 YHNNYNNPPHHQIHPPPPPHHH----IAAVGF---HKYPQNDNRDQRFNQPHYSGQQQNMIVDQS 76

  Fly    53 RRGYNDFP--GCGGSGGNGGSANNLGGGNMCHLPPMASNNSLNNLCGLSLGSGGSDDLMNDPRAS 115
            ......||  .||||.                |....|.::.:|..|                 |
plant    77 NNAPPPFPPSPCGGSS----------------LRKRRSQSATDNADG-----------------S 108

  Fly   116 NTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVL-N 179
            ...|.|..:.:..|:.::..:|...|.:....:.:|..||....|.|:.:....:...||..| .
plant   109 IAKLYVAPISKTATEYDIRQVFEKYGNVTEIILPKDKMTGERAAYCFIKYKKVEEGNAAIAALTE 173

  Fly   180 GITVRNKRL--KVSYARPGGESI--------KDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNI 234
            ..|...:.|  ||.:|....|.|        .:..|||..|.:..|..:::.:|.:||.|....:
plant   174 QFTFPGEMLPVKVRFAEAERERIGFAPVQLPDNPKLYVRCLNKQTTKMEVNEVFSRYGIIEDIYM 238

  Fly   235 LRD--KLTGRPRGVAFVRYNKREEAQEAISALNNVIP-EGGSQPLSVRLAEEHGKAKAAHFMSQM 296
            ..|  |:.   ||.|||:::.:|.|..||.|||.:.. .|..|||.||.|:.. |.:.....|..
plant   239 ALDDMKIC---RGYAFVQFSCKEMALAAIKALNGLFTIRGSDQPLIVRFADPK-KPRLGEQRSTF 299

  Fly   297 GVVPA-----------------NVPPPPPQ---------PPAHMAAAFNMMHRDGAMEKLRSLFD 335
            ...||                 |..|.||:         .|.|    |...:.....|..:.|..
plant   300 NTPPAMQHFDPNWHSQPYPQWENKEPAPPRVVQHHDFSSQPNH----FPHQNTQAVSEVHKPLHQ 360

  Fly   336 AICDAIFGLDSENFADLLDGLYRRKYHYPYLXLTPQQQQQLLQH-------QQQALGFTSSSNNS 393
            .|..|.|....::....::              |....|::..|       |.........|.::
plant   361 DIPPANFEKHQKSETASVE--------------TRSDGQKISSHSNAFHEDQNTVSSECDWSEHT 411

  Fly   394 IGNGN---------------GNDNNMLLYHQQYHQQQT--QQQRLGNVAAHNISPNGSNNNINTS 441
            ..|||               .::.:|   ::::.::||  |.:::.:...:|.|...      ..
plant   412 CPNGNKYYFHCITCESTWEKPDEYSM---YERWLKEQTRLQDEKIKSPPLNNESQEA------IE 467

  Fly   442 NTNNINFNTIRQNGVAALHYLQEQLQLQQPQDQQSQQQQ-----PLT 483
            |:..:..:.::|||           :||||....:.|:.     |:|
plant   468 NSEQVESDVLQQNG-----------ELQQPSLSTADQENNVVVYPVT 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	18/82 (22%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	29/80 (36%)
AT2G47310	NP_850472.1	RRM_SF	111..190	CDD:418427	17/78 (22%)
		RRM_SF	208..287	CDD:418427	30/81 (37%)
		WW	406..432	CDD:395320	4/25 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24012
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.970