DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sxl and Hnrnpa0

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_084148.1	Gene:	Hnrnpa0 / 77134	MGIID:	1924384	Length:	305	Species:	Mus musculus

Alignment Length:	148	Identity:	40/148 - (27%)
Similarity:	71/148 - (47%)	Gaps:	7/148 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 LIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTS--EMDSQRAIK--VLN 179
            |.:..|....::..|...|.|.|.:..|.::.:.:|..|..:.||.:::  |.|:..|..  .::
Mouse     9 LFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAVD 73

  Fly   180 GITVRNKRL--KVSYARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGR 242
            |.||..||.  :...||||..: |...|:|..|...:.:..|...|.::|::.:..|:.||.:|:
Mouse    74 GNTVELKRAVSREDSARPGAHA-KVKKLFVGGLKGDVAEGDLIEHFSQFGAVEKAEIIADKQSGK 137

  Fly   243 PRGVAFVRYNKREEAQEA 260
            .||..||.:...:.|.:|
Mouse   138 KRGFGFVYFQSHDAADKA 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	22/83 (27%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	16/58 (28%)
Hnrnpa0	NP_084148.1	RRM1_hnRNPA0	5..83	CDD:409764	19/73 (26%)
		RRM_SF	99..178	CDD:418427	16/57 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	178..211
		HnRNPA1	253..>272	CDD:402981
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	265..305
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920