DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sxl and SNRPA

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_004587.1	Gene:	SNRPA / 6626	HGNCID:	11151	Length:	282	Species:	Homo sapiens

Alignment Length:	215	Identity:	48/215 - (22%)
Similarity:	81/215 - (37%)	Gaps:	53/215 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 DPRASNTNLIVNY---LPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQ 172
            :.|.::|..|.|.   :.:|...:.|||:|...|.|....:.|..|..   |.|||.|.....:.
Human     5 ETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMR---GQAFVIFKEVSSAT 66

  Fly   173 RAIKVLNGITVRNKRLKVSYARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRD 237
            .|::.:.|....:|.:::.||:                    ||.  |.|....|:.|:::..|:
Human    67 NALRSMQGFPFYDKPMRIQYAK--------------------TDS--DIIAKMKGTFVERDRKRE 109

  Fly   238 KLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEHG-------KAKAAHFMSQ 295
            |              ::.::||. .|....:..||:.|:   :....|       ..:|...|..
Human   110 K--------------RKPKSQET-PATKKAVQGGGATPV---VGAVQGPVPGMPPMTQAPRIMHH 156

  Fly   296 MGVVPANVPPPPPQPPAHMA 315
            |...|..:|||...||..:|
Human   157 MPGQPPYMPPPGMIPPPGLA 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	22/82 (27%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	14/77 (18%)
SNRPA	NP_004587.1	RRM1_U1A	7..95	CDD:409906	26/112 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	100..132		8/46 (17%)
		RRM2_U1A	197..282	CDD:409908
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910