Protein Alignment Sxl and TRA2B

DIOPT Version :9

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: NP_004584.1
• Gene: TRA2B / 6434
• HGNCID: 10781
• Length: 288
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 70/341 - (20%)
• Similarity: 108/341 - (31%)
• Gaps: 98/341 - (28%)

  Fly    49 SSSSRRGYNDFPGCGGSGGNGGSANNLGGGNMCHLPPMASNNSLNNLCGLSLGSGGSDDLMNDPR 113
            |.|..:.|.:..  ..|....|||:  |.|......|..|.:..::....|.....|:......|
Human     2 SDSGEQNYGERE--SRSASRSGSAH--GSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSRR 62

  Fly   114 ASNTNLIVNYLPQDMTDRELYALFRAIGPIN----TCRIMRDYKTGYSFGYAFVDFTSEMDSQRA 174
            :|               |..|...|:....:    :....|||:..:|..:      |.|.::|
Human    63 SS---------------RRHYTRSRSRSRSHRRSRSRSYSRDYRRRHSHSH------SPMSTRR- 105

  Fly   175 IKVLNGITVRNKRLKVSYARPGGESIKDTN--LYVTNLPRTITDDQLDTIFGKYGSIVQKNILRD 237
                              ...|..:..|.|  |.|..|....|:..|..:|.|||.|...:|:.|
Human   106 ------------------RHVGNRANPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYD 152

  Fly   238 KLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEHGKAKAAHFMSQMGVVPAN 302
            :.:.|.||.|||.:...::|:||....|.:..:|.      |:..:....|..|
Human   153 QQSRRSRGFAFVYFENVDDAKEAKERANGMELDGR------RIRVDFSITKRPH----------- 200

  Fly   303 VPPPPPQPPAHMA-AAFNMMHRDGAMEKLRSLFDAICDAIFGLDSENF----------------- 349
                .|.|..:|. ..:....|       |..:|...|.  |.|..::
Human   201 ----TPTPGIYMGRPTYGSSRR-------RDYYDRGYDR--GYDDRDYYSRSYRGGGGGGGGWRA 252

  Fly   350 ADLLDGLYRRKYHYPY 365
            |...|.:|||:...||
Human   253 AQDRDQIYRRRSPSPY 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	10/83 (12%)
		RRM2_Hu_like	203..281	CDD:240822	25/79 (32%)
TRA2B	NP_004584.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..114		26/155 (17%)
		RRM_TRA2	117..196	CDD:409798	25/84 (30%)
		Linker	193..230		9/60 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	196..225		8/50 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	242..288		7/27 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910