Protein Alignment Sxl and RBMS2

DIOPT Version :9

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: XP_006719604.1
• Gene: RBMS2 / 5939
• HGNCID: 9909
• Length: 477
• Species: Homo sapiens
• Alignment Length: 361
• Identity: 91/361 - (25%)
• Similarity: 142/361 - (39%)
• Gaps: 83/361 - (22%)

  Fly    84 PPMASNNSLNNLCGLSLGSGGSDDLMNDPRASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRI 148
            ||..||::.|:    |.||.|:|.|      |.|||.:..|....||::|..|.:..|.|.:.:.
Human    33 PPSPSNSTPNS----SSGSNGNDQL------SKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKA 87

  Fly   149 MRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNGITVRNKRLKVSYARPGGESIKDTNLYVTNLPRT 213
            :.|..|....||.||||.|...:|:|:..|....|:.:..|.....|       ||||::|||.:
Human    88 ILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAKQQEQDP-------TNLYISNLPLS 145

  Fly   214 ITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNN---VIPEG---G 272
            :.:.:|:.:...:|.::...|||| .:|..|||.|.|....|:.:..|:..|.   ..|.|   .
Human   146 MDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPPGVPAP 209

  Fly   273 SQPLSVRLAE-------------EHGKAKAAHFMSQMGVVPANVPPPPPQPPAHMAAAFNMM-HR 323
            |.||..:.|:             ::|:|...:  :.|||:.....|..........|.:|:. :|
Human   210 SDPLLCKFADGGPKKRQNQGKFVQNGRAWPRN--ADMGVMALTYDPTTALQNGFYPAPYNITPNR 272

  Fly   324 DGAMEKLRSLFDAICDAIFGLDSENFADLLDGLYRR--------------KYHYPYL------XL 368
            ..|...|.....:...:                |:|              .:|:.||       |
Human   273 MLAQSALSPYLSSPVSS----------------YQRVTQTSPLQVPNPSWMHHHSYLMQPSGSVL 321

  Fly   369 TP-------QQQQQLLQHQQQALGFTSSSNNSIGNG 397
            ||       .|...::....|.||..|.|:....:|
Human   322 TPGMDHPISLQPASMMGPLTQQLGHLSLSSTVYADG 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	25/79 (32%)
		RRM2_Hu_like	203..281	CDD:240822	27/83 (33%)
RBMS2	XP_006719604.1	RRM1_MSSP1	49..134	CDD:240914	28/90 (31%)
		RRM2_MSSP2	135..220	CDD:240918	28/85 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910