Protein Alignment Sxl and RBMS1

DIOPT Version :9

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: XP_005246794.1
• Gene: RBMS1 / 5937
• HGNCID: 9907
• Length: 422
• Species: Homo sapiens
• Alignment Length: 428
• Identity: 104/428 - (24%)
• Similarity: 162/428 - (37%)
• Gaps: 90/428 - (21%)

  Fly    84 PPMASNNSLNNLCGLSLGSGGSDDLMNDPRASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRI 148
            ||..|..|.||....|..||. |.|      |.|||.:..||...||::|..|.:..|.|.:.:.
Human    36 PPSPSTTSSNNNSSSSSNSGW-DQL------SKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKA 93

  Fly   149 MRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNGITVRNKRLKVSYARPGGESIKDTNLYVTNLPRT 213
            :.|..|....||.||||.|...:|:|:..|....|:.:..|.....|       ||||::|||.:
Human    94 ILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDP-------TNLYISNLPLS 151

  Fly   214 ITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVI---PEGGSQP 275
            :.:.:|:.:...:|.::...||||. :|..|||.|.|....|:.:..|...|...   |.|.|.|
Human   152 MDEQELENMLKPFGQVISTRILRDS-SGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAP 215

  Fly   276 LSVRLAE--EHGKAKAAHFMSQMGVVPANVPPPPPQPPAHMAAAFNMMHRDGAMEKLRSL---FD 335
            ....|.:  :.|:.|..:         .|...|..:|          .||:|.: :|..:   :|
Human   216 TEPLLCKFADGGQKKRQN---------PNKYIPNGRP----------WHREGEV-RLAGMTLTYD 260

  Fly   336 AICDAIFGLDSENFADLLDGLYRRKYHY------------PYLXLTPQQQQQLLQHQQQALGFTS 388
            ....||           .:|.|...|..            ||:  :|....|:.:..::
Human   261 PTTAAI-----------QNGFYPSPYSIATNRMITQTSITPYIA-SPVSAYQVAKETRE------ 307

  Fly   389 SSNNSIGNGNGNDNNMLLYHQQYHQQQ-------TQQQRLGNVAAHNISPNGSN-NNINTSNTNN 445
              |...|:.....:...:..|.|..|.       :.:..:....|..|||.... ::::..:|..
Human   308 --NKYRGSAIKVQSPSWMQPQPYILQHPGAVLTPSMEHTMSLQPASMISPLAQQMSHLSLGSTGT 370

  Fly   446 INFNTIRQNGVAALHYLQEQLQLQQ---PQDQQSQQQQ 480
            ....|....|.    ||.:...:|.   |.::.|.|||
Human   371 YMPATSAMQGA----YLPQYAHMQTTAVPVEEASGQQQ 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	26/79 (33%)
		RRM2_Hu_like	203..281	CDD:240822	26/80 (33%)
RBMS1	XP_005246794.1	RRM1_MSSP1	55..140	CDD:409900	29/91 (32%)
		RRM2_MSSP1	141..225	CDD:409903	27/84 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910