DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Sxl and celf3a

DIOPT Version :9

Sequence 1:NP_001259303.1 Gene:Sxl / 3772180 FlyBaseID:FBgn0264270 Length:722 Species:Drosophila melanogaster
Sequence 2:XP_021323804.1 Gene:celf3a / 57922 ZFINID:ZDB-GENE-000501-2 Length:458 Species:Danio rerio


Alignment Length:486 Identity:106/486 - (21%)
Similarity:179/486 - (36%) Gaps:162/486 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   114 ASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDF---TSEMDSQRAI 175
            |....|.:..:|:::.:::|..:|...|.|....:::|..||...|.||:.:   .|.:.:|.|:
Zfish     4 ADAIKLFIGQIPRNLEEKDLKPIFEQFGKIYELTVIKDKYTGMHKGCAFLTYCARESALKAQNAL 68

  Fly   176 ---KVLNGITVRNKRLKVSYARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRD 237
               |.|.|:   |:.::|..|...|..  |..|:|..|.:.::|..:..:|..:|||.:..:||.
Zfish    69 HEQKTLPGM---NRPIQVKPADSEGRG--DRKLFVGMLGKQLSDADVRKMFEPFGSIEECTVLRG 128

  Fly   238 KLTGRPRGVAFVRYNKREEAQEAISAL--NNVIPEGGSQPLSVRLAE---EHGKAKAAHFMSQMG 297
            . .|..:|.|||:|....|||.|||||  :..:| |.|..|.|:.|:   |.|..:.....||:|
Zfish   129 P-DGASKGCAFVKYQSNAEAQAAISALHGSRTLP-GASSSLVVKFADTEKERGIRRMQQVASQLG 191

  Fly   298 VV-------------------------------------------------------------PA 301
            |:                                                             |:
Zfish   192 VISPMSLHLGAYNAYTQALVQQQALVAQSAYLSPVATVAAVQMQQLAALNPSSIIATPIASITPS 256

  Fly   302 NV---------------------PPP------PPQPPA-HMAAAFNMMHRDG---------AMEK 329
            :|                     |||      ||.|.| :..:|...::.:|         |::.
Zfish   257 SVCNCAVGTSTPPTIAATPVPALPPPIAVNSYPPVPAAPNGQSASEALYTNGVHPYQAQSPALDP 321

  Fly   330 LRSL------FDAICDAIFGLDSENFADLLDGLYRRKYHYPYL-XLTPQQQQQLLQHQQQALGFT 387
            |:..      :.|...|.:||..:.|.           |.|.|  ..|||.|||.|.:       
Zfish   322 LQQAYTGMQHYTATYPAAYGLVGQPFP-----------HQPTLVAQQPQQPQQLQQRE------- 368

  Fly   388 SSSNNSIGNGNGNDN-NMLLYH--QQYHQQQTQQQRL--GNVAAHNISPNGSNNNINTSNTNNIN 447
                       |.:. |:.:||  |::...:..|..|  |||.:..:..:.:.|........:.:
Zfish   369 -----------GPEGCNIFIYHLPQEFTDSEMLQMFLPFGNVISAKVFVDRATNQSKCFGFVSFD 422

  Fly   448 FNTIRQNGVAALHYLQ-----EQLQLQQPQD 473
            .....|..:.|::..|     .::||::|:|
Zfish   423 NPASAQAAIQAMNGFQIGMKRLKVQLKRPKD 453

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SxlNP_001259303.1 RRM1_SXL 117..197 CDD:241093 21/85 (25%)
RRM2_Hu_like 203..281 CDD:240822 29/79 (37%)
celf3aXP_021323804.1 RRM1_CELF3_4_5_6 2..88 CDD:241076 22/86 (26%)
RRM2_CELF3_4_5_6 93..173 CDD:241079 30/81 (37%)
Atrophin-1 <225..348 CDD:331285 17/122 (14%)
RRM3_CELF3_4_5_6 369..447 CDD:241083 14/77 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.