Protein Alignment Sxl and RBM23

DIOPT Version :9

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: XP_024305408.1
• Gene: RBM23 / 55147
• HGNCID: 20155
• Length: 515
• Species: Homo sapiens
• Alignment Length: 430
• Identity: 94/430 - (21%)
• Similarity: 141/430 - (32%)
• Gaps: 143/430 - (33%)

  Fly     2 YGNNNPGSNNNNGGYPPYGYNNKSSGGRGFG------MSHSLPSGMDTEFSFPSSSSRRGY---- 56
            |.:|...|.:|:|        |::||....|      .|.|.....|.:.|  .|..|..|
Human    78 YPSNTTSSTSNSG--------NETSGSSTIGETSKKKRSRSHNKSRDRKRS--RSRDRDRYRRRN 132

  Fly    57 --NDFPG--CGGSG-------GNGGSANNLGGGNMCHL--PPMASNNSLNNLCGLSLGSGGS--- 105
              :..||  |....       |:...:.:....:..|.  ||:|:        |...|...|
Human   133 SRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLAT--------GYRYGHSKSPHF 189

  Fly   106 ----------DDLMNDPRASNT----NLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGY 156
                      |:|..:.|.:.|    .|.....|:|:.|     .|.|:|.:...||:.|..:..
Human   190 REKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLED-----FFSAVGKVRDVRIISDRNSRR 249

  Fly   157 SFGYAFVDF-------------------------TSEMDSQRAIKVLNGITVRNKRLKVSYARPG 196
            |.|.|:|:|                         .|:.:..|...:.|.:...|          |
Human   250 SKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGN----------G 304

  Fly   197 GESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAI 261
            |    ...|||.:|...||:|.|..||..:|.|....:::|..|||.:|..|:.::..|.|:.|:
Human   305 G----PMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRAL 365

  Fly   262 SALNN-----------------------VIPE----------GGSQPLSVRLAEEHG------KA 287
            ..||.                       ..|:          ||...|..:|||..|      .|
Human   366 EQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGIQLPSTAA 430

  Fly   288 KAAHFMSQMGVVPAN--VPPPPPQPPAHMAAAFNMMHRDG 325
            .||...:|...:..|  ||.....|.|...:..:...|:|
Human   431 AAAAAAAQAAALQLNGAVPLGALNPAALTGSLGHGKGREG 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	20/108 (19%)
		RRM2_Hu_like	203..281	CDD:240822	27/110 (25%)
RBM23	XP_024305408.1	RRM	143..514	CDD:330708	75/355 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910