Protein Alignment Sxl and RBM47

DIOPT Version :9

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: NP_001092104.1
• Gene: RBM47 / 54502
• HGNCID: 30358
• Length: 593
• Species: Homo sapiens
• Alignment Length: 510
• Identity: 97/510 - (19%)
• Similarity: 160/510 - (31%)
• Gaps: 205/510 - (40%)

  Fly   119 LIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNGITV 183
            :.|..:|:|:.:.||..:|.|:|.|...|:|.|: .|.:.|||||.:..:.:::||::.||...:
Human    73 VFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDF-DGKNRGYAFVMYCHKHEAKRAVRELNNYEI 136

  Fly   184 RNKRL------------------------------------------------------------ 188
            |..||
Human   137 RPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEY 201

  Fly   189 -------------------------KVSYARPG---GESIKDT--NLYVTNLPRTITDDQLDTIF 223
                                     .|.:|.|.   .|.:.:|  .|||.||....|:|.:...|
Human   202 ESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKSF 266

  Fly   224 GKY--GSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEHGK 286
            |::  |.:.:...:||        .|||.:..||:|..|::.||....||..  |.|.||:...|
Human   267 GQFNPGCVERVKKIRD--------YAFVHFTSREDAVHAMNNLNGTELEGSC--LEVTLAKPVDK 321

  Fly   287 AKAAHFMSQM---GVVPANVPPPPPQPPAHMAAAFNMMHRDGAMEKLRSLFDAICDAIFGLDSEN 348
            .:.:.:....   |...|      .|.|:::.:                     ||.
Human   322 EQYSRYQKAARGGGAAEA------AQQPSYVYS---------------------CDP-------- 351

  Fly   349 FADLLDGLYRRKYH-YPYLXLT-PQQQQQLLQHQQQALGFTSSSNNSIG----------NGNGND 401
                    |...|: |||. |. |.:...:.....:..|..::.|.:.|          .|.|
Human   352 --------YTLAYYGYPYNALIGPNRDYFVKAGSIRGRGRGAAGNRAPGPRGSYLGGYSAGRG-- 406

  Fly   402 NNMLLYHQQYHQQQTQQQRLGNVAAHNISPNGSNNNINTSNTNNINFNTIRQNGVAA-------- 458
                 .:.:||:.:.:||..|    :.:.|   |..|.|.|...|...|:....:.|
Human   407 -----IYSRYHEGKGKQQEKG----YELVP---NLEIPTVNPVAIKPGTVAIPAIGAQYSMFPAA 459

  Fly   459 ----------LHYLQEQLQ--LQQPQDQQSQQQQPL----------TMPSSPPFQ 491
                      :|.::..:.  ..||....:......          |:.:.||||
Human   460 PAPKMIEDGKIHTVEHMISPIAVQPDPASAAAAAAAAAAAAAAVIPTVSTPPPFQ 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	28/165 (17%)
		RRM2_Hu_like	203..281	CDD:240822	26/81 (32%)
RBM47	NP_001092104.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		hnRNP-R-Q	21..593	CDD:273732	97/510 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910