DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sxl and tra2a

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	XP_012819962.1	Gene:	tra2a / 448073	XenbaseID:	XB-GENE-492325	Length:	341	Species:	Xenopus tropicalis

Alignment Length:	169	Identity:	42/169 - (24%)
Similarity:	64/169 - (37%)	Gaps:	47/169 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 RGFGMSHSLPSGMDTEFSFPSSSSRRGYNDFPGCGGSGGNGGSANNLGGGNMCHLPPMASNNSLN 93
            |....|||......:....|....||..:..|.......||..||          |.       .
Frog    65 RSRSRSHSRKRRSKSRSYTPEYRRRRSRSHSPMSNRRRHNGSRAN----------PD-------P 112

  Fly    94 NLC----GLSLGSGGSDDLMNDPRASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKT 154
            |:|    ||||.:                          |:|:|..:|...||::...::.|.:|
Frog   113 NICIGVFGLSLYT--------------------------TERDLREVFSRYGPLSGVNVVYDQRT 151

  Fly   155 GYSFGYAFVDFTSEMDSQRAIKVLNGITVRNKRLKVSYA 193
            |.|.|:|||.|....||:.|::..||:.:..:|::|.|:
Frog   152 GRSRGFAFVYFERIEDSREAMEHANGMELDGRRIRVDYS 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	23/77 (30%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822
tra2a	XP_012819962.1	RRM	<98..>190	CDD:223796	33/134 (25%)
tra2a	XP_012819962.1	RRM_TRA2	115..192	CDD:240809	28/102 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910