Protein Alignment Sxl and Syp

DIOPT Version :9

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: NP_001262777.1
• Gene: Syp / 42460
• FlyBaseID: FBgn0038826
• Length: 761
• Species: Drosophila melanogaster
• Alignment Length: 679
• Identity: 131/679 - (19%)
• Similarity: 201/679 - (29%)
• Gaps: 270/679 - (39%)

  Fly    84 PPMASNNSLNNLCGLSLGSGGSDDLMNDPRASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRI 148
            ||....|...|.|.:..|.                     :|:||.:.||..||...|.|...|:
  Fly   194 PPHWEGNVPGNGCEVFCGK---------------------IPKDMYEDELIPLFENCGIIWDLRL 237

  Fly   149 MRDYKTGYSFGYAFVDFTSEMDSQRAIKVLN----------GITV-------------------- 183
            |.|..||.:.|||||.||:...:..|::.||          |:|:
  Fly   238 MMDPMTGTNRGYAFVTFTNREAAVNAVRQLNDFEIRTGKKIGVTISFNNHRLFVGNIPKNRDRDE 302

  Fly   184 -------------------------RNK-----------------------RLK-------VSYA 193
                                     :|:                       |:|       |.:|
  Fly   303 LIEEFSKHAPGLYEVIIYSSPDDKKKNRGFCFLEYESHKAASLAKRRLGTGRIKVWGCDIIVDWA 367

  Fly   194 RPGGESIKDTN-----LYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNK 253
            .|..|..:.|.     |||.||.:.:::|:|...|.:||.:.:...::|        .||:.:..
  Fly   368 DPQEEPDEQTMSKVKVLYVRNLTQDVSEDKLKEQFEQYGKVERVKKIKD--------YAFIHFED 424

  Fly   254 REEAQEAISALNNVIPEGGSQPLSVRLA---------EEHGKAKAAHFMSQMGVVPA-----NVP 304
            |:.|.||:..||.  .|.|:..:.|.||         ||..:|:....|..|...|.     .:.
  Fly   425 RDSAVEAMRGLNG--KEIGASNIEVSLAKPPSDKKKKEEILRARERRMMQMMQARPGIVGFETLS 487

  Fly   305 PPPPQPPAHMAAAFNMMHRDGAMEKLRS----LFDAICD----------AIFGLDSENFADL--- 352
            |.....|.|.:.......|.||...||:    .:|...|          ..||.:...:.|:
  Fly   488 PYRNLSPTHPSIMSLTPMRPGARMPLRTPIPREYDYFYDFFGFSDYRQGGSFGNNVSYYDDMYRW 552

  Fly   353 LDGLYRRKYHYPYLXLTPQQQQQLLQHQQQALGFTSSSNNSIGNGNGNDNNMLLYHQQYHQQQTQ 417
            :||.| ..|.||                           |..|.|:|...
  Fly   553 IDGDY-NYYDYP---------------------------NGGGGGSGGGG--------------- 574

  Fly   418 QQRLGNVAAHNISP---NGSNNNINTSNTNNINFNTIRQNGVAALHYLQEQLQLQQPQDQQSQQQ 479
                |:|:...:.|   .||.|:...|...:...:.   :|.:|           .|......:.
  Fly   575 ----GSVSGGTVLPLSAGGSQNSPMASGQRSARGSA---SGPSA-----------SPSLMGVGRG 621

  Fly   480 QPLTMPSSPPFQQQSRQSHHNGSSSTLGNQLLAISNNNSFNNNSNQSNSFTGNYSNGSAFTSNGA 544
            ..:|:|       :.|.....||.|.||.|                    |...:.|:|..:..|
  Fly   622 HGITVP-------RGRVVGQRGSISRLGAQ--------------------TVPQAAGAAAAAGQA 659

  Fly   545 IS-----GSNFPNNPTSSGNFTNNSTNSNPTNSGHFASNLAGSSNFTNHLSGSNNYTNSNGNFTS 604
            .:     |:.....|.::|.|    ....||..         |:..|.|:....|..
  Fly   660 AAAVAQRGATGQGAPAATGGF----RGVLPTRP---------SARGTQHVKPLQNLP-------- 703

  Fly   605 NAASSSNFSNNAASSTNYSKNCSSGVVGN 633
             ......|.....:..:..:...||::||
  Fly   704 -VVGKRKFDGGHQNPADVKRRYPSGLIGN 731

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	32/164 (20%)
		RRM2_Hu_like	203..281	CDD:240822	23/82 (28%)
Syp	NP_001262777.1	RRM1_hnRNPR_like	205..283	CDD:240695	28/98 (29%)
		RRM2_hnRNPR_like	286..367	CDD:240696	4/80 (5%)
		RRM3_hnRNPR_like	381..452	CDD:240697	24/80 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910