DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sxl and rbm14b

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	XP_021333123.1	Gene:	rbm14b / 402858	ZFINID:	ZDB-GENE-040426-2455	Length:	560	Species:	Danio rerio

Alignment Length:	259	Identity:	66/259 - (25%)
Similarity:	105/259 - (40%)	Gaps:	54/259 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 RASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKV 177
            :.....|.|..|..|.|..||.|:|.:.|.:.:|.::|.        :|||....|..::|||:.
Zfish     3 KGHTVKLFVGNLALDTTQEELSAIFESYGQVVSCSVLRQ--------FAFVHLQGEGAAERAIRE 59

  Fly   178 LNGITVRNKRLKVSYARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGR 242
            |||...:.:.|.|..:|  |..:..|.::|.||....|.:.|..:|..:|.:::    .||:
Zfish    60 LNGREFKGRNLVVEESR--GRPLHSTKVFVGNLSSMCTTEDLQELFQTFGKVLE----CDKV--- 115

  Fly   243 PRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEH----------------------- 284
             :|.|||....:|:|.:||.||:....:|  :||||.|::..
Zfish   116 -KGYAFVHMENKEDALQAIEALHGTSFKG--RPLSVELSKVQPSKQTPTGKIPCVSCGKQGHYAG 177

  Fly   285 ----GKAKAAHFMSQMGVVPANVPPPPPQPPAHMAAAFNMMHRDGAMEKLRSLFDAICDAIFGL 344
                ||.....:.||..|:.|........|.....:..|.::.       .|.||....|:.||
Zfish   178 ECPAGKPTLEQYQSQAAVLAAAAAAAAGLPLQVQQSVHNSVYN-------TSTFDPTYAALTGL 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	25/79 (32%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	25/77 (32%)
rbm14b	XP_021333123.1	RRM1_CoAA	7..75	CDD:241052	24/75 (32%)
		RRM1_2_CoAA_like	84..149	CDD:240789	23/74 (31%)
		AIR1	<150..>187	CDD:331526	3/36 (8%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910