Protein Alignment Sxl and tia1

DIOPT Version :9

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: XP_012814227.2
• Gene: tia1 / 394890
• XenbaseID: XB-GENE-1002876
• Length: 389
• Species: Xenopus tropicalis
• Alignment Length: 494
• Identity: 98/494 - (19%)
• Similarity: 177/494 - (35%)
• Gaps: 134/494 - (27%)

  Fly   106 DDLMNDPRASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMD 170
            :||   ||    .|.|..|.:|:|:..:..:|..:||..:|:::.|  |..:..|.||:|.....
 Frog     3 EDL---PR----TLYVGNLSRDVTEPLILQVFSQLGPCKSCKMIMD--TAGNDPYCFVEFFEHRH 58

  Fly   171 SQRAIKVLNGITVRNKRLKVSYARPGGESIKDTN---------------LYVTNLPRTITDDQLD 220
            :..::..:||..:..|.:||::|.......||.|               ::|.:|...||.|.:.
 Frog    59 AAASLAAMNGRKIMGKEVKVNWATTPSSQKKDANSSSVVSTLRSQDHFHVFVGDLSPEITTDDIK 123

  Fly   221 TIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEHG 285
            ..|..:|.|....:::|..||:.:|..||.:..:.:|:.||:.:       |.|.|..|
 Frog   124 AAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQM-------GGQWLGGR------ 175

  Fly   286 KAKAAHFMSQMGVVPANVPPPPPQPPAHMAAAFNMMHRDGAMEKLRSLFDAICDAIFGLDSENFA 350
                     |:....|...||.|: ..:.:....:.:.:...:...|.....|..:       .:
 Frog   176 ---------QIRTNWATRKPPAPK-STYESNTKQLTYEEVVNQSSPSNCTVYCGGV-------TS 223

  Fly   351 DLLDGLYRRKYHYPYLXLTPQQQQQLLQHQQQALGFTSSSNNSIGNGNGNDNNMLLYHQQYHQQQ 415
            .|.:.|.|:.:. |:     .|..::.....:...|...|:                    |:.
 Frog   224 GLTEQLMRQTFS-PF-----GQIMEVRVFPDKGYSFVRFSS--------------------HES- 261

  Fly   416 TQQQRLGNVAAHNI-SPNGSNNNINTSNTNNINFNTIRQNGVAALHYLQEQLQLQQPQDQQSQQQ 479
                     |||.| |.||                |..:..|...::.:|...:..|..|.|:..
 Frog   262 ---------AAHAIVSVNG----------------TTIEGHVVKCYWGKETPDMLNPVQQVSEAS 301

  Fly   480 QPLTMPSSPPFQQQSRQSHHNGSSSTLGNQLLAISNNNSFNNNSNQSNSFTGNYSNGSAFTSNGA 544
            | ::.|  ||:.|..:   ..|.:..:|          .:..|..|..:: |.|  |.|::..|
 Frog   302 Q-ISFP--PPYGQWGQ---WYGGAQQIG----------QYVPNGWQMPAY-GVY--GQAWSQQG- 346

  Fly   545 ISGSNFPNNPTSSGNFT--NNSTNSNPTNSGHFASNLAG 581
                 :...|:|:..:.  |......|..:|...:|..|
 Frog   347 -----YSQTPSSAATWVGPNYGVQPQPGQNGTLITNQTG 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	21/79 (27%)
		RRM2_Hu_like	203..281	CDD:240822	22/92 (24%)
tia1	XP_012814227.2	RRM1_TIA1	8..81	CDD:410027	20/74 (27%)
		RRM2_TIA1	104..181	CDD:410030	22/98 (22%)
		RRM3_TIAR	214..286	CDD:241064	18/130 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910