Protein Alignment Sxl and hnrnpl

DIOPT Version :9

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: NP_957393.1
• Gene: hnrnpl / 394074
• ZFINID: ZDB-GENE-040426-710
• Length: 536
• Species: Danio rerio
• Alignment Length: 569
• Identity: 117/569 - (20%)
• Similarity: 177/569 - (31%)
• Gaps: 209/569 - (36%)

  Fly    14 GGYPPYGYNNKSSGGRGFGMSHSLPSGMDTEFSFPSSSSRRGYND-------------------- 58
            |.|  ||     .|||......:...|||||          ||||
Zfish     6 GHY--YG-----DGGRATKRQKTDSDGMDTE----------GYNDPHKTLPSLVVHVRGLIDGIT 53

  Fly    59 -----------------------------FPGCGGSGGNGGSANNLGGGNMCHLPPMASNNSLNN 94
                                         |....|:......|||    |..::   |...|..|
Zfish    54 EADLVEALQEFGTISYVVLMPKKRQALVEFEDMNGASNAVTYANN----NQIYI---AGRPSYIN 111

  Fly    95 LCGLSLGSGGSDDLMNDPRASNTNLIVNYLP--QDMTDRELYALFRAIGPINTCRIMRDYKTGYS 157
            .......|..:|.  :|.|:.|..|::..:.  ..:|...||.:....||:....|.|  |.|..
Zfish   112 YSTSQKISRPTDS--DDTRSVNNVLLLTIMNPIYPITSDVLYTICNNCGPVQRIVIFR--KNGVQ 172

  Fly   158 FGYAFVDFTSEMDSQRAIKVLNGITVRNK--RLKVSYARPGGESI----KDTNLYVTNLPRTITD 216
               |.|:|.|...:|||...|||..:.:.  .||:.||:|...::    :||..| ||...:..|
Zfish   173 ---AMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDY-TNPNLSGQD 233

  Fly   217 DQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLA 281
            ...|   |.:.:....|       ..|        |||:. |.|:  |.:..||.||.
Zfish   234 ADAD---GNWNNSQDPN-------ANP--------NKRQR-QPAL--LGDHPPEYGSP------- 270

  Fly   282 EEHGKAKAAHFMSQMGVVPANVPPPP------------------------------PQPPAHMAA 316
                :....|:....|      ||||                              |.||.:.|
Zfish   271 ----QGGYGHYDDTYG------PPPPPPHYEGRRMGPPIGRGRGVPRYGGAQYGHGPPPPDYNA- 324

  Fly   317 AFNMMHRDGAMEKLRSLFDAI---CDAIFGLDSENFADLLDGLYRRKYHYPYLXLTPQQQQQLLQ 378
                 |.|..:..:..| |.:   .|.:|     |...|...:.|.|:               ::
Zfish   325 -----HADSPVVMVYGL-DPVKINADRVF-----NIFCLYGNVERVKF---------------MK 363

  Fly   379 HQQQALGFTSSSNNSIGNGNGNDNNMLLYHQQYHQQQTQQQRLGNVAAHNISPNGS--------- 434
            .:..|.........::.....:.||.:|:.|:.:...::||.:....::.:. :||
Zfish   364 SKPGAAMVEMGDCYAVDRAVSHLNNTMLFGQKLNVCVSKQQAIMPGQSYQLE-DGSCSFKDFHGY 427

  Fly   435 -NNNINTSN---TNNIN--------FNTIRQNGVAALHYLQEQLQLQQP 471
             ||...||.   .|.|.        ||:...:.|.|...:.|:|.::.|
Zfish   428 RNNRFTTSEQAAKNRIQQPSNVLHFFNSQPDSSVEAFSEICEELGIKSP 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	25/83 (30%)
		RRM2_Hu_like	203..281	CDD:240822	19/77 (25%)
hnrnpl	NP_957393.1	hnRNP-L_PTB	39..534	CDD:273733	101/519 (19%)
		RRM1_hnRNPL	39..118	CDD:241224	9/85 (11%)
		RRM2_hnRNPL	128..227	CDD:241229	31/104 (30%)
		Bindin	265..>322	CDD:251078	13/73 (18%)
		RRM_SF	330..403	CDD:302621	13/93 (14%)
		RRM4_hnRNPL	446..529	CDD:241148	7/31 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910