DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sxl and hnrnpa1a

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	XP_021335234.1	Gene:	hnrnpa1a / 393467	ZFINID:	ZDB-GENE-040426-1546	Length:	445	Species:	Danio rerio

Alignment Length:	179	Identity:	44/179 - (24%)
Similarity:	76/179 - (42%)	Gaps:	39/179 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 LIVNYLPQDMTDRELYALFRAIGPINTC----------------------------RIMRDYKTG 155
            |.:..|..:.||..|.|.|...|.:..|                            ::|||..|.
Zfish    40 LFIGGLSFETTDESLRAHFEQWGTLTDCVVSPSAAIHMLMYEREEHLKVAGFLYCSQVMRDPNTK 104

  Fly   156 YSFGYAFVDFTS--EMDS---QRAIKVLNGITVRNKRL--KVSYARPGGES-IKDTNLYVTNLPR 212
            .|.|:.||.::|  |:|:   .|..|| :|..|..||.  :...::||..| :|  .::|..:..
Zfish   105 RSRGFGFVTYSSVGEVDAAMDARPHKV-DGRAVEPKRAVSREDSSKPGAHSTVK--KMFVGGIKE 166

  Fly   213 TITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAI 261
            ...::.|...||::|.|.:.||:.:|.:.:.||.||:.::..:.....:
Zfish   167 DTDEEHLREYFGQFGKIDEVNIMTEKNSDKRRGFAFITFDDHDAVDRIV 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	28/112 (25%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	13/59 (22%)
hnrnpa1a	XP_021335234.1	RRM_SF	36..144	CDD:327398	27/104 (26%)
		RRM_SF	157..233	CDD:327398	14/61 (23%)
		HnRNPA1	376..>392	CDD:314495
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920