Protein Alignment Sxl and Pabpc1l

DIOPT Version :9

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: NP_001107551.1
• Gene: Pabpc1l / 381404
• MGIID: 1922908
• Length: 607
• Species: Mus musculus
• Alignment Length: 577
• Identity: 117/577 - (20%)
• Similarity: 200/577 - (34%)
• Gaps: 196/577 - (33%)

  Fly    21 YNNKSSGGRGFGMSH----SLPSGMDTE-----FSFPSS--SSRRGYNDFPGCGGSGGNGGSANN 74
            ::::..|.|..||.:    :|.:.:|.:     ||...|  ||:..||:.    ||.|.|
Mouse    86 WSHRDPGLRKSGMGNIFIKNLENSIDNKALYDTFSTFGSILSSKVVYNEH----GSRGFG----- 141

  Fly    75 LGGGNMCHLPP-MASNNSLNNLCGLSLGSGGSDDLMNDPRA--------------------SNTN 118
                 ..|... .|:..::|.:.|:         |:||.:.                    ..||
Mouse   142 -----FVHFETHEAAQKAINTMNGM---------LLNDRKVFVGHFKSRQKREAELGARALGFTN 192

  Fly   119 LIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNGITV 183
            :.|..|..::.::.|..||...|.:.:.::||| ..|.|.|:.||:|....::|:|:..:||..|
Mouse   193 IYVKNLHANVDEQRLQDLFSQFGNMQSVKVMRD-SNGQSRGFGFVNFEKHEEAQKAVDHMNGKEV 256

  Fly   184 RNKRLKVSYARPGGE------------------SIKDTNLYVTNLPRTITDDQLDTIFGKYGSIV 230
            ..:.|.|..|:...|                  ..:..||||.||..:|.|::|..:|..||.|.
Mouse   257 SGQLLYVGRAQKRAERQSELKRRFEQMKQERQNRYQGVNLYVKNLDDSINDERLKEVFSTYGVIT 321

  Fly   231 QKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEHGKAKAAHFMSQ 295
            ...::.:  :...:|..||.::..|||.:|::.:|..|.  |::||.|.||:...:.||
Mouse   322 SAKVMTE--SSHSKGFGFVCFSSPEEATKAVTEMNGRIV--GTKPLYVALAQRKEERKA------ 376

  Fly   296 MGVVPANVPPPPPQPPAHMAAAFNMMHRDGAMEKLRSLFDAICDAIFGLDSENFADLLDGLYRRK 360
                                                                    :|...|||:
Mouse   377 --------------------------------------------------------ILTNQYRRR 385

  Fly   361 YHYPYLXLTPQQQQQLL----QHQQQALGFTSSSNNSI-------GNGNGNDNNM---------- 404
            ..:|.| ...|....||    |...||:.::|.|...:       ...:|..:..
Mouse   386 PSHPVLSSFQQPTSYLLPAVPQSTAQAVYYSSGSITPMQPDPRWTAQPHGPPSTCPPAASVVQPL 450

  Fly   405 ---------LLYHQQYHQQQTQQQRLGNVAAHNISPNGSNNNINTSNTNNINFNTIRQNGVAALH 460
                     |....|...|....||:.|:......|.|..::|...       ..:...|.:|:|
Mouse   451 STTQHPCIHLRGASQVSSQVPHTQRVVNIGTQTTGPGGEGSSIPGQ-------LLVPHRGTSAVH 508

  Fly   461 YLQ--EQLQLQQPQDQQSQQQQPLT--MPSSPPFQQQSRQSHHNGSSSTLGNQLLAI 513
            ...  ::..:..|      ..||||  |.::.|..:|.:.         :|.:|.::
Mouse   509 SAHGVQESAVYVP------GHQPLTVSMLAAAPLHEQKQM---------IGERLYSL 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	25/79 (32%)
		RRM2_Hu_like	203..281	CDD:240822	26/77 (34%)
Pabpc1l	NP_001107551.1	PABP-1234	11..596	CDD:130689	117/577 (20%)
		RRM1_I_PABPs	12..91	CDD:240824	0/4 (0%)
		RRM2_I_PABPs	97..172	CDD:240825	22/97 (23%)
		RRM3_I_PABPs	190..269	CDD:240826	25/79 (32%)
		RRM4_I_PABPs	293..370	CDD:240827	28/80 (35%)
		PABP	529..595	CDD:279051	5/31 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910