DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sxl and PABPC1L2A

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_001012995.1	Gene:	PABPC1L2A / 340529	HGNCID:	27989	Length:	200	Species:	Homo sapiens

Alignment Length:	152	Identity:	47/152 - (30%)
Similarity:	85/152 - (55%)	Gaps:	4/152 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 NLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNGIT 182
            :|.|..|..::|:..||..|...|||.:.||.||..|..|.|||:|::...:|::||::.||...
Human     3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALETLNFDV 67

  Fly   183 VRNKRLKVSYAR--PGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRG 245
            ::.:.:::.:::  |........|:::.||.:||.:..|..||..:|:|:...:..|:  ..|:|
Human    68 IKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDE--KGPKG 130

  Fly   246 VAFVRYNKREEAQEAISALNNV 267
            ..||.:.|:|.|:.||..:|.:
Human   131 YGFVHFQKQESAERAIDVMNGM 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	26/80 (33%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	21/65 (32%)
PABPC1L2A	NP_001012995.1	PABP-1234	2..>196	CDD:130689	47/152 (31%)
PABPC1L2A	NP_001012995.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	170..200
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910